An efficient synthesis of 2-amino-5-chloro-3-pyridinecarbox-aldehyde and 5-amino-2-chloro-4-pyridinecarboxaldehyde

被引：0

作者：

Hou, Chuan-Jin ^{[1
,2
]}

Guo, Wei-Lei ^{[1
]}

Liu, Xiao-Ning ^{[1
]}

Yang, Da-Wei ^{[1
]}

机构：

[1] Dalian Polytech Univ, Sch Chem & Mat, Dalian 116034, Peoples R China

[2] Minist Agr, Key Lab Pesticide Chem & Applicat, Beijing 100193, Peoples R China

来源：

HETEROCYCLIC COMMUNICATIONS | 2011年 / 17卷 / 1-2期

关键词：

amino; chloro; naphthyridine; pyridinecarboxaldehyde; synthesis; FACILE SYNTHESIS; 1,8-NAPHTHYRIDINES; 2-AMINONICOTINALDEHYDE; AMINOPYRIDINES; FORMYLATION; DERIVATIVES; ANALOGS; AGENTS;

D O I：

10.1515/HC.2011.004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Efficient synthetic routes to the title compounds 2-amino-5-chloro-3-pyridinecarboxaldehyde (1a) and 5-amino-2-chloro-4-pyridinecarboxaldehyde (1b) are reported. Both compounds are important substrates in the synthesis of naphthyridine derivatives.

引用

页码：21 / 23

页数：3

共 50 条

[21] An efficient synthesis of 5-chloro-2, 3, 4-trifluorobenzoic acid
Yu, Shuitao
Zhou, Weiyou
Xia, Zhengjun
Lin, Song
Chen, Zaixin
JOURNAL OF CHEMICAL RESEARCH, 2015, (06) : 326 - 327
[22] SYNTHESIS OF 2-C-14-3-AMINO-1-CHLORO-5-METHYLHEXAN-2-ONE HYDROCHLORIDE
LEWIS, NJ
HES, J
YIP, P
CAZER, FD
JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 1977, 13 (04): : 487 - 490
[23] BACTERIAL DEGRADATION OF 5-AMINO-4-CHLORO-2-PHENYL-3(2H)-PYRIDAZINONE
FRENNE, ED
EBERSPAC.J
LINGENS, F
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1973, 33 (02): : 357 - 363
[24] Synthesis and crystal structure of 2-amino-4-chloro-5-(4'-methylbenzyl)-6-methylpyrimidine
Guo Wan-Cheng
Liu Xing-Hai
Chen Pei-Quan
Song Hai-Bin
Li Zheng-Ming
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY, 2007, 26 (09) : 1005 - 1008
[25] 4-{2-[(5-Chloro-2-hydroxybenzylidene)amino]ethyl}benzenesulfonamide
Chohan, Zahid H.
Shad, Hazoor A.
Tahir, M. Nawaz
Khan, Islam Ullah
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O725 - U1512
[26] SYNTHESIS, SPECTRAL PROPERTIES, AND PESTICIDAL ACTIVITY OF 4-AMINO(ALKYLAMINO, DIALKYLAMINO)-5-CHLORO-2-SUBSTITUTED-3-OXO-2H-PYRIDAZINES AND 5-AMINO(ALKYLAMINO, DIALKYLAMINO)-4-CHLORO-2-SUBSTITUTED-3-OXO-2H-PYRIDAZINES
KONECNY, V
KOVAC, S
VARKONDA, S
COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 1985, 50 (02) : 492 - 502
[27] CHLORINE NQR IN 3-AMINO-2-CHLOROPYRIDINE AND 2-CHLORO-5-NITROPYRIDINE
BASAVARAJU, SP
DEVARAJ, N
INDUMATHY, A
SRIDHARAN, KR
RAMAKRISHNA, J
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 1983, 39 (01): : 15 - 17
[28] (E)-4-Amino-N′-(5-chloro-2-hydroxybenzylidene)benzohydrazide
Shi, Zhong-Feng
Li, Jia-Ming
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2012, 68 : O1546 - +
[29] {5-Chloro-2-[(4-chlorobenzylidene)-amino]phenyl}(phenyl) methanone
Aslam, Muhammad
Anis, Itrat
Afza, Nighat
Yasmeen, Shazia
Yousuf, Sammer
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O644 - U1678
[30] {5-Chloro-2-[(4-nitrobenzylidene)amino]phenyl}(phenyl)methanone
Aslam, M.
Anis, I.
Afza, N.
Nelofar, A.
Yousuf, S.
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O3215 - U529

← 1 2 3 4 5 →