An efficient synthesis of 2-amino-5-chloro-3-pyridinecarbox-aldehyde and 5-amino-2-chloro-4-pyridinecarboxaldehyde

被引：0

作者：

Hou, Chuan-Jin ^{[1
,2
]}

Guo, Wei-Lei ^{[1
]}

Liu, Xiao-Ning ^{[1
]}

Yang, Da-Wei ^{[1
]}

机构：

[1] Dalian Polytech Univ, Sch Chem & Mat, Dalian 116034, Peoples R China

[2] Minist Agr, Key Lab Pesticide Chem & Applicat, Beijing 100193, Peoples R China

来源：

HETEROCYCLIC COMMUNICATIONS | 2011年 / 17卷 / 1-2期

关键词：

amino; chloro; naphthyridine; pyridinecarboxaldehyde; synthesis; FACILE SYNTHESIS; 1,8-NAPHTHYRIDINES; 2-AMINONICOTINALDEHYDE; AMINOPYRIDINES; FORMYLATION; DERIVATIVES; ANALOGS; AGENTS;

D O I：

10.1515/HC.2011.004

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Efficient synthetic routes to the title compounds 2-amino-5-chloro-3-pyridinecarboxaldehyde (1a) and 5-amino-2-chloro-4-pyridinecarboxaldehyde (1b) are reported. Both compounds are important substrates in the synthesis of naphthyridine derivatives.

引用

页码：21 / 23

页数：3

共 50 条

[1] ESTABLISHMENT OF ANALYSIS METHOD IN THE SYNTHESIS OF ISOMER 4-AMINO-2-CHLORO-3-NITROPYRIDINE AND 4-AMINO-2-CHLORO-5-NITROPYRIDINE
Zhang, Y.
Song, Y. X.
Zhao, S. C.
Song, H. W.
Yang, J. X.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2016, 118 : 94 - 94
[2] 2-Amino-3-chloro-5-nitrobenzamide
Wardell, James L.
Tiekink, Edward R. T.
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O991 - +
[3] A CONVENIENT SYNTHESIS OF METHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE
EHRENKAUFER, RL
SCRIPKO, JG
HOFFMAN, PL
ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL, 1992, 24 (01) : 64 - 66
[4] 2-Amino-5-methylpyridinium 4-chloro-benzoate
Thanigaimani, Kaliyaperumal
Farhadikoutenaei, Abbas
Arshad, Suhana
Razak, Ibrahim Abdul
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2013, 69 : O134 - +
[5] 2-Amino-2′-chloro-5-methylbenzophenone
Xing, ZY
Liu, HM
Wu, L
Zhang, WQ
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2005, 61 : O3796 - O3797
[6] 2-Amino-5-bromopyridinium 5-chloro-2-hydroxybenzoate
Thanigaimani, Kaliyaperumal
Khalib, Nuridayanti Che
Arshad, Suhana
Razak, Ibrahim Abdul
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2013, 69 : O537 - +
[7] Improved Synthesis of 2-Chloro-3-amino-4-methylpyridine
Zhao, Qian
Chen, Han-Geng
Qian, Chao
Chen, Xin-Zhi
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2013, 50 (01) : 145 - 148
[8] A concise synthesis of 2-chloro-3-amino-4-methylpyridine
Ge, Xin
Chen, Han-geng
Cao, Chang-hui
Liu, Jin-qiang
Qian, Chao
Chen, Xin-zhi
RESEARCH ON CHEMICAL INTERMEDIATES, 2011, 37 (06) : 599 - 604
[9] A concise synthesis of 2-chloro-3-amino-4-methylpyridine
Xin Ge
Han-geng Chen
Chang-hui Cao
Jin-qiang Liu
Chao Qian
Xin-zhi Chen
Research on Chemical Intermediates, 2011, 37 : 599 - 604
[10] Synthesis of [(4-Chloro-5H-1,2,3-dithiazol-5-ylidene)amino]azines
Koutentis, Panayiotis A.
Koyioni, Maria
Michaelidou, Sophia S.
MOLECULES, 2011, 16 (11) : 8992 - 9002

← 1 2 3 4 5 →