SERRATED POLYPS OF THE COLORECTUM: HISTOLOGICAL CLASSIFICATION AND CLINICAL SIGNIFICANCE

被引:0
|
作者
Orlowska, Janina [1 ]
机构
[1] Ctr Oncol, Med Ctr Postgrad Educ, Dept Gastroenterol & Hepatol, Histopathol Lab, PL-02781 Warsaw, Poland
关键词
serrated polyps; hyperplastic polyp; sessile serrated polyp; serrated adenoma; HYPERPLASTIC ADENOMATOUS POLYPS; ABERRANT CRYPT FOCI; METAPLASTIC POLYP; CANCER; CARCINOMA; COLON; ADENOCARCINOMA; NEOPLASIA; PATHWAY; FLAT;
D O I
暂无
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Serrated polyps of the colorectum are heterogeneous lesions, a subset of which is now regarded as the precursor of colorectal cancer with DNA microsatellite instability. The serrated pathway encompassing hyperplastic aberrant crypt foci, hyperplastic polyps, sessile serrated polyps (adenomas), mixed polyps, and traditional serrated adenomas, with a meticulous review of their up-to-date histological classifications, is presented. Some remarks concerning genetics of serrated polyps and the mechanism leading to carcinoma development are also included.
引用
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页码:8 / 22
页数:15
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