Immunoglobulin G4-Related Disease in the Head and Neck: Two Case Reports and Literature Review

被引：0
|
作者：
Baf, Morteza Mazloum Farsi [1 ]
Sahebari, Maryam [1 ]
Khazaeni, Kamran [2 ]
Rezaieyazdi, Zahra [1 ]
机构：
[1] Mashhad Univ Med Sci, Ghaem Hosp, Fac Med, RDRC, Mashhad 9919991760, Iran
[2] Mashhad Univ Med Sci, Ghaem Hosp, Fac Med, Sinus & Surg Endoscop Res Ctr, Mashhad 9919991760, Iran
来源：
ARCHIVES OF RHEUMATOLOGY | 2015年 / 30卷 / 02期
关键词：
Immunoglobulin G4-related disease; Mikulicz's syndrome; Sjogren's disease; IGG4-RELATED SYSTEMIC-DISEASE; AUTOIMMUNE PANCREATITIS; SCLEROSING DISEASE; MIKULICZS-DISEASE; CLINICOPATHOLOGICAL-ENTITY; CASTLEMANS-DISEASE; THYROIDITIS; PATHOLOGY; LYMPHADENOPATHY; MANIFESTATIONS;
D O I：
10.5606/ArchRheumatol.2015.5105
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Immunoglobulin G4-related disease (IgG4-related disease) is a fibroinflammatory disorder defined by elevated serum IgG4 level and plasma cells tissue infiltration accompanied by fibrosis or sclerosis. In this article, we report two patients of IgG4 syndrome: a 60-year-old male with complaints of nasal congestion, rhinitis, anosmia and hearing loss, and a 28-year-old female with bilateral orbital and parotid gland swelling. Histopathological findings and high serum IgG4 level confirmed diagnosis of IgG4-related disease. Both patients were treated successfully with glucocorticoids and methotrexate. Herein, we also review clinical presentations of IgG4-related disease in head and neck, and related diagnostic and therapeutic approach.
引用
收藏
页码：172 / 177
页数：6
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