Intermediate role of gut microbiota in vitamin B nutrition and its influences on human health

被引:70
|
作者
Wan, Zhijie [1 ]
Zheng, Jianheng [2 ]
Zhu, Zhigang [2 ]
Sang, Lan [1 ]
Zhu, Jinwei [1 ]
Luo, Shizheng [1 ]
Zhao, Yixin [1 ]
Wang, Ruirui [1 ]
Zhang, Yicui [1 ]
Hao, Kun [1 ]
Chen, Liang [2 ]
Du, Jun [2 ]
Kan, Juntao [2 ]
He, Hua [1 ]
机构
[1] China Pharmaceut Univ, Ctr Drug Metab & Pharmacokinet, Nanjing, Peoples R China
[2] Nutrilite Hlth Inst, Shanghai, Peoples R China
来源
FRONTIERS IN NUTRITION | 2022年 / 9卷
关键词
vitamin B; gut microbiota; interaction; absorption; human health; PANTOTHENIC-ACID CONTENT; CHAIN FATTY-ACIDS; FOLIC-ACID; INTESTINAL-ABSORPTION; BIOTIN TRANSPORT; NICOTINIC-ACID; FUNCTIONAL-CHARACTERIZATION; COGNITIVE IMPAIRMENT; FOLATE PRODUCTION; ESCHERICHIA-COLI;
D O I
10.3389/fnut.2022.1031502
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Vitamin B consists of a group of water-soluble micronutrients that are mainly derived from the daily diet. They serve as cofactors, mediating multiple metabolic pathways in humans. As an integrated part of human health, gut microbiota could produce, consume, and even compete for vitamin B with the host. The interplay between gut microbiota and the host might be a crucial factor affecting the absorbing processes of vitamin B. On the other hand, vitamin B supplementation or deficiency might impact the growth of specific bacteria, resulting in changes in the composition and function of gut microbiota. Together, the interplay between vitamin B and gut microbiota might systemically contribute to human health. In this review, we summarized the interactions between vitamin B and gut microbiota and tried to reveal the underlying mechanism so that we can have a better understanding of its role in human health.
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页数:21
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