Tricin from a Malagasy connaraceous plant with potent antihistaminic activity

被引：48

作者：

Kuwabara, H ^{[1
]}

Mouri, K ^{[1
]}

Otsuka, H ^{[1
]}

Kasai, R ^{[1
]}

Yamasaki, K ^{[1
]}

机构：

[1] Hiroshima Univ, Dept Pharmacognosy, Div Med Chem, Grad Sch Biomed Sci,Minami Ku, Hiroshima 7348551, Japan

来源：

JOURNAL OF NATURAL PRODUCTS | 2003年 / 66卷 / 09期

关键词：

D O I：

10.1021/np030020p

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The bioassay-guided separation of a Malagasy plant, Agelaea pentagyna, led to the isolation of a flavonoid, tricin (1), with potent inhibitory activity toward exocytosis from antigen-stimulated rat leukemia basophils (RBL-2H3). The structure-activity relationships among structurally related natural and synthetic flavonoids are also discussed.

引用

页码：1273 / 1275

页数：3

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