Tricin from a Malagasy connaraceous plant with potent antihistaminic activity

被引：48
|
作者：
Kuwabara, H [1 ]
Mouri, K [1 ]
Otsuka, H [1 ]
Kasai, R [1 ]
Yamasaki, K [1 ]
机构：
[1] Hiroshima Univ, Dept Pharmacognosy, Div Med Chem, Grad Sch Biomed Sci,Minami Ku, Hiroshima 7348551, Japan
来源：
JOURNAL OF NATURAL PRODUCTS | 2003年 / 66卷 / 09期
关键词：
D O I：
10.1021/np030020p
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
The bioassay-guided separation of a Malagasy plant, Agelaea pentagyna, led to the isolation of a flavonoid, tricin (1), with potent inhibitory activity toward exocytosis from antigen-stimulated rat leukemia basophils (RBL-2H3). The structure-activity relationships among structurally related natural and synthetic flavonoids are also discussed.
引用
收藏
页码：1273 / 1275
页数：3
相关论文
共 50 条
  • [1] Preparation and Tumor Inhibitory Activity of Tricin from Carex Meyeriana Kunth
    Cui, Baiji
    Sun, Jie
    Chang, Sheng
    Zhang, Hongmei
    Li, Yawei
    Feng, Xianmin
    Guo, Zengjun
    MOLECULES, 2024, 29 (19):
  • [2] Biological Activity of Luteolin Glycosides and Tricin from Sasa senanensis Rehder
    Matsuta, Tomohiko
    Sakagami, Hiroshi
    Satoh, Kazue
    Kanamoto, Taisei
    Terakubo, Shigemi
    Nakashima, Hideki
    Kitajima, Madoka
    Oizumi, Hiroshi
    Oizumi, Takaaki
    IN VIVO, 2011, 25 (05): : 757 - 762
  • [3] Pregnane and pregnane glycosides from the Malagasy plant, Cynanchum aphyllum
    Kanchanapoom, T
    Kasai, R
    Ohtani, K
    Andriantsiferana, M
    Yamasaki, K
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2002, 50 (08) : 1031 - 1034
  • [4] Tricin, 4′,5,7-trihydroxy-3′,5′-dimethoxyllavone, exhibits potent antiangiogenic activity in vitro
    Han, Jang Mi
    Kwon, Ho Jeong
    Jung, Hye Jin
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2016, 49 (04) : 1497 - 1504
  • [5] Mizolastine: antihistaminic activity from preclinical data to clinical evaluation
    Simons, FER
    CLINICAL AND EXPERIMENTAL ALLERGY, 1999, 29 : 3 - 8
  • [6] Potent antiallergic/antiasthmatic activity of plant extract 4397
    Nath, A.
    Maurya, R.
    Raghubir, R.
    INDIAN JOURNAL OF PHARMACOLOGY, 2008, 40 : 155 - 155
  • [7] Clerodane and labdane diterpene glycosides from a Malagasy endemic plant, Cussonia racemosa
    Liva, RRH
    Kasai, R
    Yamasaki, K
    PHYTOCHEMISTRY, 2002, 60 (04) : 339 - 343
  • [8] Antileishmanial Activity and Immunomodulatory Effects of Tricin Isolated from Leaves of Casearia arborea (Salicaceae)
    Santos, Augusto L.
    Yamamoto, Eduardo S.
    Passero, Luiz Felipe D.
    Laurenti, Marcia D.
    Martins, Ligia F.
    Lima, Marta L.
    Uemi, Miriam
    Soares, Marisi G.
    Lago, Joao Henrique G.
    Tempone, Andre G.
    Sartorelli, Patricia
    CHEMISTRY & BIODIVERSITY, 2017, 14 (05)
  • [9] ent-Kaurane diterpenoid glycosides from a Malagasy endemic plant, Cussonia vantsilana
    Harinantenaina, L
    Kasai, R
    Yamasaki, K
    PHYTOCHEMISTRY, 2002, 61 (04) : 367 - 372
  • [10] P-glycoprotein inhibitory activity of two phenolic compounds, (-)-syringaresinol and tricin from Sasa borealis
    Jeong, Yeon Hee
    Chung, Soo Yeon
    Han, Ah-Reum
    Sung, Min Kyung
    Jang, Dae Sik
    Lee, Jun
    Kwon, Youngjoo
    Lee, Hwa Jeong
    Seo, Eun-Kyoung
    CHEMISTRY & BIODIVERSITY, 2007, 4 (01) : 12 - 16
12345