Sequencing DNA using mass spectrometry for ladder detection

被引：43
|
作者：
Taranenko, NI
Allman, SL
Golovlev, VV
Taranenko, NV
Isola, NR
Chen, CH [1 ]
机构：
[1] Oak Ridge Natl Lab, Div Life Sci, Oak Ridge, TN 37831 USA
[2] Yale Univ, Med Ctr, New Haven, CT USA
来源：
NUCLEIC ACIDS RESEARCH | 1998年 / 26卷 / 10期
关键词：
D O I：
10.1093/nar/26.10.2488
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Sequencing of DNA fragments of 130 and 200 bp using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry for DNA ladder detection was demonstrated. With further improvement in mass resolution and detection sensitivity, mass spectrometry shows great promise for routine DNA sequencing in the future.
引用
收藏
页码：2488 / 2490
页数：3
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