Update on the Neuropsychiatry of Substance Use Disorders

被引：2

作者：

Kolodner, George ^{[1
,2
]}

Koliatsos, Vassilis E. ^{[3
,4
,5
,6
]}

机构：

[1] Kolmac Outpatient Recovery Ctr, 3919 Natl Dr, Burtonsville, MD 20910 USA

[2] Univ Maryland, Sch Med, Georgetown Univ, College Pk, MD 20742 USA

[3] Johns Hopkins Univ, Sch Med, Dept Pathol Neuropathol, Baltimore, MD USA

[4] Johns Hopkins Univ, Sch Med, Dept Neurol, Baltimore, MD 21205 USA

[5] Johns Hopkins Univ, Sch Med, Dept Psychiat & Behav Sci, Baltimore, MD 21205 USA

[6] Sheppard & Enoch Pratt Hosp, Neuropsychiat Program, Sheppard Pratt Hlth Syst, 6501 North Charles St, Baltimore, MD 21204 USA

来源：

PSYCHIATRIC CLINICS OF NORTH AMERICA | 2020年 / 43卷 / 02期

关键词：

Substance use disorders; Opioids; Cannabis; Drugs; Craving; Buprenorphine; Naltrexone; Acamprosate; RANDOMIZED CONTROLLED-TRIAL; DOUBLE-BLIND; CANNABIS; ABSTINENCE; METHADONE;

D O I：

10.1016/j.psc.2020.02.011

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

This article reviews some of the recent discoveries about how neurobiological processes contribute to the understanding and treatment of substance use disorders. Particular focus is given to cannabis, opioids, and designer drugs. Important areas addressed include triggers and cravings, the central roles of dopamine and stress, and the endocannabinoid system. Clinical relevance of these findings for withdrawal management and relapse prevention is discussed. Also highlighted are issues related to the opioid epidemic and consequences both of continuing federal prohibition of cannabis as well as its state-by-state relaxation.

引用

页码：291 / +

页数：15

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