A highly efficient three-component coupling of aldehyde, terminal alkyne, and amine via C-H activation catalyzed by reusable immobilized copper in organic-inorganic hybrid materials under solvent-free reaction conditions

被引：99
|
作者：
Li, Pinhua [1 ]
Wang, Lei [1 ,2 ]
机构：
[1] Huaibei Coal Teachers Coll, Dept Chem, Huaibei 235000, Anhui, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
来源：
TETRAHEDRON | 2007年 / 63卷 / 25期
基金：
中国国家自然科学基金;
关键词：
D O I：
10.1016/j.tet.2007.04.032
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Recycling copper( I) immobilized on organic-inorganic hybrid material behaves as a very efficient heterogeneous catalyst in the three-component Mannich coupling reaction of aldehydes, terminal alkynes, and amines via C-H activation to afford the corresponding products in good to excellent yields under solvent-free reaction conditions. (c) 2007 Elsevier Ltd. All rights reserved.
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页码：5455 / 5459
页数：5
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