Organocatalytic enantioselective (3+2) cycloaddition using stable azomethine ylides

被引：58

作者：

Fernandez, Naiara ^{[1
]}

Carrillo, Luisa ^{[1
]}

Vicario, Jose L. ^{[1
]}

Badia, Dolores ^{[1
]}

Reyes, Efraim ^{[1
]}

机构：

[1] Univ Basque Country, Dept Organ Chem 2, Bilbao 48080, Spain

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 45期

关键词：

1,3-DIPOLAR CYCLOADDITIONS; DERIVATIVES;

D O I：

10.1039/c1cc15671c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We have developed a highly efficient procedure for carrying out the catalytic enantioselective (3+2) cycloaddition between enals and stable azomethine ylides such as isoquinolinium and phthalizinium methylides. Under the optimized reaction conditions highly substituted chiral pyrroloisoquinolines and pyrrolophthalazines have been obtained in high yields and excellent diastereo- and enantioselectivities.

引用

页码：12313 / 12315

页数：3

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