Synthesis and pharmacological screening of some 1,4-dihydropyridine and their derivatives for anticonvulsant activity

被引:0
|
作者
Pattan, Shashikant R. [1 ]
Purohit, S. S. [1 ]
Rasal, V. P. [2 ]
Mallya, S. [3 ]
Marihal, S. C. [3 ]
Khade, A. B.
Paschapur, M. S. [2 ]
机构
[1] KLESs Coll Pharm, Dept Med Chem, Belgaum 590010, India
[2] KLESs Coll Pharm, Dept Pharmacol, Belgaum 590010, India
[3] Goa Coll Pharm, Dept Pharmacol, Panaji 403001, Goa, India
关键词
anticonvulsant; antihypertensive; 1,4-dihydropyridine;
D O I
暂无
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A new series of 1,4-dihydropyridine and their derivatives have been synthesized and the structures of the compounds have been confirmed by IR and NMR. The title compounds are evaluated for anticonvulsant activity by maximal electroshock method. Some of these compounds have been found to exhibit excellent anticonvulsant activity.
引用
收藏
页码:626 / 629
页数:4
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