Transmissibility of livestock-associated methicillin-resistant Staphylococcus aureus (ST398) in Dutch hospitals

被引：86
|
作者：
Wassenberg, M. W. M. [1 ,2 ]
Bootsma, M. C. J. [3 ,4 ]
Troelstra, A. [2 ]
Kluytmans, J. A. J. W. [5 ,6 ]
Bonten, M. J. M. [2 ,3 ]
机构：
[1] Univ Med Ctr Utrecht, Dept Internal Med & Infect Dis, Utrecht, Netherlands
[2] Univ Med Ctr Utrecht, Dept Med Microbiol, Utrecht, Netherlands
[3] Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands
[4] Univ Utrecht, Dept Math, Fac Sci, Utrecht, Netherlands
[5] Amphia Hosp, Lab Microbiol & Infect Control, Breda, Netherlands
[6] Vrije Univ Amsterdam Med Ctr, Dept Med Microbiol & Infect Control, Amsterdam, Netherlands
来源：
CLINICAL MICROBIOLOGY AND INFECTION | 2011年 / 17卷 / 02期
关键词：
Livestock-associated MRSA; methicillin-resistant Staphylococcus aureus; nosocomial transmission; ST398;
D O I：
10.1111/j.1469-0691.2010.03260.x
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
P>We quantified nosocomial transmission rates of sequence type (ST) 398 methicillin-resistant Staphylococcus aureus (MRSA) (an emerging livestock-associated MRSA clone) and non-ST398 MRSA isolates in patients hospitalized without infection control measures in 51 Dutch hospitals. Identification of 174 index patients initiated 139 post-exposure screenings of 9925 persons. There were 65 genotype-confirmed secondary cases (three and 62 for ST398 and non-ST398 MRSA, respectively), yielding a relative transmission risk for ST398 MRSA of 0.28 (95% CI 0.09-0.90), which was not sensitive to adjustment for duration of hospitalization at time of detection. Nosocomial transmission of ST398 MRSA is 72% less likely than that of non-ST398 MRSA strains.
引用
收藏
页码：316 / 319
页数：4
相关论文
共 50 条
  • [1] Transmissibility of Livestock-associated Methicillin-Resistant Staphylococcus aureus
    Hetem, David J.
    Bootsma, Martin C. J.
    Troelstra, Annet
    Bonten, Marc J. M.
    [J]. EMERGING INFECTIOUS DISEASES, 2013, 19 (11) : 1797 - 1802
  • [2] The occurrence and distribution of livestock-associated methicillin-resistant Staphylococcus aureus ST398 on German dairy farms
    Schnitt, A.
    Lienen, T.
    Wichmann-Schauer, H.
    Cuny, C.
    Tenhagen, B-A
    [J]. JOURNAL OF DAIRY SCIENCE, 2020, 103 (12) : 11806 - 11819
  • [3] Diversity of accessory genome of human and livestock-associated ST398 methicillin resistant Staphylococcus aureus strains
    Hallin, M.
    De Mendonca, R.
    Denis, O.
    Lefort, A.
    El Garch, F.
    Butaye, P.
    Hermans, K.
    Struelens, M. J.
    [J]. INFECTION GENETICS AND EVOLUTION, 2011, 11 (02) : 290 - 299
  • [4] Methicillin-Resistant Staphylococcus aureus ST398, Italy
    Soavi, Laura
    Stellini, Roberto
    Signorini, Liana
    Antonini, Benvenuto
    Pedroni, Palmino
    Zanetti, Livio
    Milanesi, Bruno
    Pantosti, Annalisa
    Matteelli, Alberto
    Pan, Angelo
    Carosi, Giampiero
    [J]. EMERGING INFECTIOUS DISEASES, 2010, 16 (02) : 346 - 348
  • [5] Outbreak of Methicillin-Resistant Staphylococcus aureus ST398 in a Dutch Nursing Home
    Verkade, Erwin
    Bosch, Thijs
    Hendriks, Yvonne
    Kluytmans, Jan
    [J]. INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 2012, 33 (06): : 624 - 626
  • [6] Real-time PCR to distinguish livestock-associated (ST398) from non-livestock-associated (methicillin-resistant) Staphylococcus aureus
    van Meurs, M. L. J. G. M.
    Schellekens, J. J. A.
    de Neeling, A. J.
    Duim, B.
    Schneeberger, P. M.
    Hermans, M. H. A.
    [J]. INFECTION, 2013, 41 (02) : 339 - 346
  • [7] Real-time PCR to distinguish livestock-associated (ST398) from non-livestock-associated (methicillin-resistant) Staphylococcus aureus
    M. L. J. G. M. van Meurs
    J. J. A. Schellekens
    A. J. de Neeling
    B. Duim
    P. M. Schneeberger
    M. H. A. Hermans
    [J]. Infection, 2013, 41 : 339 - 346
  • [8] Whole genome analysis of a livestock-associated methicillin-resistant Staphylococcus aureus ST398 isolate from a case of human endocarditis
    Schijffelen, Maarten J.
    Boel, C. H. Edwin
    van Strijp, Jos A. G.
    Fluit, Ad C.
    [J]. BMC GENOMICS, 2010, 11
  • [9] Whole-Genome Sequence of Livestock-Associated ST398 Methicillin-Resistant Staphylococcus aureus Isolated from Humans in Canada
    Golding, George R.
    Bryden, Louis
    Levett, Paul N.
    McDonald, Ryan R.
    Wong, Alice
    Graham, Morag R.
    Tyler, Shaun
    Van Domselaar, Gary
    Mabon, Philip
    Kent, Heather
    Butaye, Patrick
    Smith, Tara C.
    Kadlec, Kristina
    Schwarz, Stefan
    Weese, Scott J.
    Mulvey, Michael R.
    [J]. JOURNAL OF BACTERIOLOGY, 2012, 194 (23) : 6627 - 6628
  • [10] Whole genome analysis of a livestock-associated methicillin-resistant Staphylococcus aureus ST398 isolate from a case of human endocarditis
    Maarten J Schijffelen
    CH Edwin Boel
    Jos AG van Strijp
    Ad C Fluit
    [J]. BMC Genomics, 11
12345