In Vitro Cell Based Cytotoxicity and T Cell Activation Assays to Assess Safety and Efficacy of Engineered T Cell Therapies

被引:0
|
作者
Holt, Sanne [1 ]
Vermond, Sophie [1 ]
Hazenoot, Monique [1 ]
Overman, Jeroen [1 ]
Aarbiou, Jamil [1 ]
DeGroot, Jeroen [1 ]
机构
[1] Charles River Labs, Early Discovery Biol, Leiden, Netherlands
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
1192
引用
收藏
页码:515 / 515
页数:1
相关论文
共 50 条
  • [1] In vitro cell based cytotoxicity and T cell activation assays to assess safety and efficacy of engineered T cell therapies
    Holt, Sanne
    Vermond, Sophie
    Hazenoot, Monique Hazenoot
    Overman, Jeroen
    Aarbiou, Jamil Aarbiou
    DeGroot, Jeroen DeGroot
    [J]. CANCER RESEARCH, 2020, 80 (16)
  • [2] PRIMARY OR IPSC-DERIVED CELL-BASED CYTOTOXICITY ASSAYS TO ASSESS POTENTIAL SAFETY RISKS OF ENGINEERED T CELL THERAPIES IN VITRO
    Vermond, Sophie
    Hazenoot, Monique
    McLaughlin, Rene
    de Munnik, Sabrina
    Guadagnoli, Marco
    Moiset, Gemma
    Holt, Sanne
    Vlaming, Marijn
    [J]. JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 9 : A156 - A156
  • [3] Primary or iPSC-derived cell-based cytotoxicity assays to assess potential safety risks of engineered T cell therapies in vitro.
    Holt, Sanne L.
    Vermond, Sophie
    Hazenoot, Monique
    McLaughlin, Rene
    Guadagnoli, Marco
    Vlaming, Marijn
    [J]. CANCER RESEARCH, 2021, 81 (13)
  • [4] In vitro efficacy and safety studies to support engineered T cell therapies
    Vermond, Sophie
    Quist, Benita
    de Munnik, Sabrina
    Hazenoot, Monique
    Avramescu, Madalina
    McLaughlin, Rene
    Moiset, Gemma
    Vlaming, Marijn
    [J]. CANCER RESEARCH, 2022, 82 (12)
  • [5] In vitro binding, efficacy and safety studies to support engineered T cell therapies
    Vermond, Sophie
    Quist, Benita
    Hazenoot, Monique
    McLaughlin, Rene
    Lopez, David Cobeta
    Jayanth, Namrata
    Verkaar, Folkert
    Aziz, Omar
    Vlaming, Maria Lh
    De Munnik, Sabrina
    Moiset, Gemma
    [J]. CANCER RESEARCH, 2023, 83 (07)
  • [6] IN VITRO EFFICACY STUDIES TO SUPPORT ENGINEERED T CELL THERAPIES
    de Munnik, Sabrina
    Hazenoot, Monique
    Vermond, Sophie
    McLaughlin, Rene
    Guadagnoli, Marco
    Moiset, Gemma
    Holt, Sann
    Vlaming, Marijn
    [J]. JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 9 : A157 - A157
  • [7] In vitro efficacy studies to support engineered T cell therapies.
    Holt, Sanne L.
    Vermond, Sophie
    Hazenoot, Monique
    McLaughlin, Rene
    Guadagnoli, Marco
    Vlaming, Marijn
    [J]. CANCER RESEARCH, 2021, 81 (13)
  • [8] Nonclinical safety assessment of engineered T cell therapies
    Lebrec, Herve
    Maier, Curtis C.
    Maki, Kazushige
    Ponce, Rafael
    Shenton, Jacintha
    Green, Shon
    [J]. REGULATORY TOXICOLOGY AND PHARMACOLOGY, 2021, 127
  • [9] Engineered T cell therapies
    Field, Anne-Christine
    Qasim, Waseem
    [J]. EXPERT REVIEWS IN MOLECULAR MEDICINE, 2015, 17
  • [10] Exploiting T cell signaling to optimize engineered T cell therapies
    Wang, Haopeng
    Song, Xianming
    Shen, Lianjun
    Wang, Xinxin
    Xu, Chenqi
    [J]. TRENDS IN CANCER, 2022, 8 (02): : 123 - 134