PRIMARY OR IPSC-DERIVED CELL-BASED CYTOTOXICITY ASSAYS TO ASSESS POTENTIAL SAFETY RISKS OF ENGINEERED T CELL THERAPIES IN VITRO

被引:0
|
作者
Vermond, Sophie [1 ]
Hazenoot, Monique [1 ]
McLaughlin, Rene [1 ]
de Munnik, Sabrina [1 ]
Guadagnoli, Marco [1 ]
Moiset, Gemma [1 ]
Holt, Sanne [1 ]
Vlaming, Marijn [1 ]
机构
[1] Charles River Labs, Leiden, Netherlands
关键词
D O I
10.1136/jitc-2021-SITC2021.148
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
148
引用
收藏
页码:A156 / A156
页数:1
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  • [1] Primary or iPSC-derived cell-based cytotoxicity assays to assess potential safety risks of engineered T cell therapies in vitro.
    Holt, Sanne L.
    Vermond, Sophie
    Hazenoot, Monique
    McLaughlin, Rene
    Guadagnoli, Marco
    Vlaming, Marijn
    [J]. CANCER RESEARCH, 2021, 81 (13)
  • [2] In Vitro Cell Based Cytotoxicity and T Cell Activation Assays to Assess Safety and Efficacy of Engineered T Cell Therapies
    Holt, Sanne
    Vermond, Sophie
    Hazenoot, Monique
    Overman, Jeroen
    Aarbiou, Jamil
    DeGroot, Jeroen
    [J]. MOLECULAR THERAPY, 2020, 28 (04) : 515 - 515
  • [3] In vitro cell based cytotoxicity and T cell activation assays to assess safety and efficacy of engineered T cell therapies
    Holt, Sanne
    Vermond, Sophie
    Hazenoot, Monique Hazenoot
    Overman, Jeroen
    Aarbiou, Jamil Aarbiou
    DeGroot, Jeroen DeGroot
    [J]. CANCER RESEARCH, 2020, 80 (16)
  • [4] IN VITRO POTENCY ASSAYS TO ASSESS THE FUNCTION OF CELL-BASED THERAPIES
    Pentakota, K.
    Montelongo, S.
    Beddard, R.
    Jones, S.
    Srinivasan, A.
    [J]. CYTOTHERAPY, 2023, 25 (06) : S202 - S203
  • [5] Cell-based cytotoxicity assays for engineered nanomaterials safety screening: exposure of adipose derived stromal cells to titanium dioxide nanoparticles
    Xu, Yan
    Hadjiargyrou, M.
    Rafailovich, Miriam
    Mironava, Tatsiana
    [J]. JOURNAL OF NANOBIOTECHNOLOGY, 2017, 15
  • [6] Cell-based cytotoxicity assays for engineered nanomaterials safety screening: exposure of adipose derived stromal cells to titanium dioxide nanoparticles
    Yan Xu
    M. Hadjiargyrou
    Miriam Rafailovich
    Tatsiana Mironava
    [J]. Journal of Nanobiotechnology, 15
  • [7] Cell-Based Therapy for Fibrosing Interstitial Lung Diseases, Current Status, and Potential Applications of iPSC-Derived Cells
    Nakamura, Yusuke
    Niho, Seiji
    Shimizu, Yasuo
    [J]. CELLS, 2024, 13 (11)
  • [8] Cell-Based Therapy for Canavan Disease Using Human iPSC-Derived NPCs and OPCs
    Feng, Lizhao
    Chao, Jianfei
    Tian, E.
    Li, Li
    Ye, Peng
    Zhang, Mi
    Chen, Xianwei
    Cui, Qi
    Sun, Guihua
    Zhou, Tao
    Felix, Gerardo
    Qin, Yue
    Li, Wendong
    Meza, Edward David
    Klein, Jeremy
    Ghoda, Lucy
    Hu, Weidong
    Luo, Yonglun
    Dang, Wei
    Hsu, David
    Gold, Joseph
    Goldman, Steven A.
    Matalon, Reuben
    Shi, Yanhong
    [J]. ADVANCED SCIENCE, 2020, 7 (23)
  • [9] In vitro cell-based assays for evaluation of antioxidant potential of plant-derived products
    Nascimento da Silva, Luis Claudio
    Bezerra Filho, Clovis Macedo
    de Paula, Raiana Apolinario
    Silva e Silva, Cristiane Santos
    Oliveira de Souza, Larissa Isabela
    da Silva, Marcia Vanusa
    dos Santos Correia, Maria Tereza
    Bressan Queiroz de Figueiredo, Regina Celia
    [J]. FREE RADICAL RESEARCH, 2016, 50 (08) : 801 - 812
  • [10] In vitro efficacy and safety studies to support engineered T cell therapies
    Vermond, Sophie
    Quist, Benita
    de Munnik, Sabrina
    Hazenoot, Monique
    Avramescu, Madalina
    McLaughlin, Rene
    Moiset, Gemma
    Vlaming, Marijn
    [J]. CANCER RESEARCH, 2022, 82 (12)