A Novel Control Method for Rotary Blood Pumps as Left Ventricular Assist Device Utilizing Aortic Valve State Detection

被引：8
|
作者：
Petukhov, Dmitry [1 ]
Korn, Leonie [2 ]
Walter, Marian [2 ]
Telyshev, Dmitry [1 ,3 ]
机构：
[1] Natl Res Univ Elect Technol, Zelenograd 124498, Russia
[2] Rhein Westfal TH Aachen, Med Informat Technol, D-52074 Aachen, Germany
[3] Sechenov First Moscow State Med Univ, Moscow 119991, Russia
来源：
BIOMED RESEARCH INTERNATIONAL | 2019年 / 2019卷
关键词：
PHYSIOLOGICAL CONTROL-SYSTEM; SUPPORT; IDENTIFICATION;
D O I：
10.1155/2019/1732160
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
A novel control method for rotary blood pumps is proposed relying on two different objectives: regulation of pump flow in accordance with desired value and the maintenance of partial support with an open aortic valve by the variation of pump speed. The estimation of pump flow and detection of aortic valve state was performed with mathematical models describing the first- and second generation of Sputnik rotary blood pumps. The control method was validated using a cardiovascular system model. The state of the aortic valve was detected with a mean accuracy of 91% for Sputnik 1 and 96.2% for Sputnik 2 when contractility, heart rate, and systemic vascular resistance was changed. In silico results for both pumps showed that the proposed control method can achieve the desired pump flow level and maintain the open state of the aortic valve by periodically switching between two objectives under contractility, heart rate, and systemic vascular resistance changes. The proposed method showed its potential for safe operation without adverse events and for the improvement of chances for myocardial recovery.
引用
收藏
页数：12
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