liver transplantation;
biliary complications;
living donor;
anastomosis;
bile leakage;
RECONSTRUCTION;
MANAGEMENT;
RECIPIENTS;
SIZE;
D O I:
10.1111/j.1477-2574.2011.00401.x
中图分类号:
R57 [消化系及腹部疾病];
学科分类号:
摘要:
Background: Biliary complications that developed after right lobe liver transplantation from living donors were studied in a single centre. Methods: From 2004 to 2010, 200 consecutive living donor right lobe liver transplantations were performed. The database was evaluated retrospectively. Biliary complications were diagnosed according to clinical, biochemical and radiological tests. The number of biliary ducts in the transplanted graft, the surgical techniques used for anastomosis, biliary strictures and bile leakage rates were analysed. Results: Of a total of 200 grafts, 117 invloved a single bile duct, 77 had two bile ducts and in six grafts there were three bile ducts. In 166 transplants, the anastomosis was performed as a single duct to duct, in 21 transplants double duct to ducts, in one transplant, three duct to ducts and in 12 transplants as a Roux-en-Y reconstruction. In all, 40 bile leakages (20%) and 17 biliary strictures (8.5%) were observed in 49 patients resulting in a total of 57 biliary complications (28.5%). Seventeen patients were re-operated (12 as a result of bile leakages and five owing to biliary strictures). Conclusion: Identification of more than one biliary orifice in the graft resulted in an increase in the complication rates. In grafts containing multiple orifices, performing multiple duct-to-duct (DD) or Roux-en-Y anastomoses led to a lower number of complications.
机构:
Apollo Special Hosp, HPB & Liver Transplant Surg Unit, Lake View Rd, Madurai 625019, Tamil Nadu, IndiaApollo Special Hosp, HPB & Liver Transplant Surg Unit, Lake View Rd, Madurai 625019, Tamil Nadu, India
Jegadeesan, Madhusudhanan
Goyal, Neerav
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机构:
Indraprastha Apollo Hosp, Ctr Liver & Biliary Sci, Delhi Mathura Rd, New Delhi 110076, IndiaApollo Special Hosp, HPB & Liver Transplant Surg Unit, Lake View Rd, Madurai 625019, Tamil Nadu, India
Goyal, Neerav
Rastogi, Harsh
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机构:
Indraprastha Apollo Hosp, Dept Radiol, New Delhi, IndiaApollo Special Hosp, HPB & Liver Transplant Surg Unit, Lake View Rd, Madurai 625019, Tamil Nadu, India
Rastogi, Harsh
Gupta, Subash
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机构:
Indraprastha Apollo Hosp, Ctr Liver & Biliary Sci, Delhi Mathura Rd, New Delhi 110076, IndiaApollo Special Hosp, HPB & Liver Transplant Surg Unit, Lake View Rd, Madurai 625019, Tamil Nadu, India
机构:
Niigata Univ, Div Digest & Gen Surg, Grad Sch Med & Dent Sci, Niigata 9518510, JapanNiigata Univ, Div Digest & Gen Surg, Grad Sch Med & Dent Sci, Niigata 9518510, Japan
Sato, Y
Yamamoto, S
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Niigata Univ, Div Digest & Gen Surg, Grad Sch Med & Dent Sci, Niigata 9518510, JapanNiigata Univ, Div Digest & Gen Surg, Grad Sch Med & Dent Sci, Niigata 9518510, Japan
Yamamoto, S
Takeishi, T
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Niigata Univ, Div Digest & Gen Surg, Grad Sch Med & Dent Sci, Niigata 9518510, JapanNiigata Univ, Div Digest & Gen Surg, Grad Sch Med & Dent Sci, Niigata 9518510, Japan
Takeishi, T
Oya, H
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Niigata Univ, Div Digest & Gen Surg, Grad Sch Med & Dent Sci, Niigata 9518510, JapanNiigata Univ, Div Digest & Gen Surg, Grad Sch Med & Dent Sci, Niigata 9518510, Japan
Oya, H
Nakatsuka, H
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Niigata Univ, Div Digest & Gen Surg, Grad Sch Med & Dent Sci, Niigata 9518510, JapanNiigata Univ, Div Digest & Gen Surg, Grad Sch Med & Dent Sci, Niigata 9518510, Japan
Nakatsuka, H
Watanabe, T
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Niigata Univ, Div Digest & Gen Surg, Grad Sch Med & Dent Sci, Niigata 9518510, JapanNiigata Univ, Div Digest & Gen Surg, Grad Sch Med & Dent Sci, Niigata 9518510, Japan
Watanabe, T
Hatakeyama, K
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Niigata Univ, Div Digest & Gen Surg, Grad Sch Med & Dent Sci, Niigata 9518510, JapanNiigata Univ, Div Digest & Gen Surg, Grad Sch Med & Dent Sci, Niigata 9518510, Japan