A historical review of XDR tuberculosis in the Western Cape province of South Africa

被引：0
|
作者：
Symons, Gregory [2 ,4 ]
Shean, Karen [2 ,4 ]
Pietersen, Elize [2 ,4 ]
Smit, Richard van Zyl [2 ,4 ]
Pool, Lititia [2 ,4 ]
Davids, Malika [2 ,4 ]
Wilcox, Paul [2 ,4 ]
Dheda, Keertan [1 ,3 ]
机构：
[1] Univ Cape Town, Lung Infect & Immun Unit, UCT Lung Inst, ZA-7700 Rondebosch, South Africa
[2] Univ Cape Town, Dept Med, UCT Lung Inst, ZA-7700 Rondebosch, South Africa
[3] Univ Cape Town, Inst Infect Dis & Mol Med, ZA-7700 Rondebosch, South Africa
[4] Univ Cape Town, Lung Infect & Immun Unit, Div Pulmonol, ZA-7700 Rondebosch, South Africa
来源：
SAMJ SOUTH AFRICAN MEDICAL JOURNAL | 2011年 / 101卷 / 09期
关键词：
MULTIDRUG-RESISTANT TUBERCULOSIS; DRUGS;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
There are limited data on the temporal relationship between the regional introduction of multidrug-resistant tuberculosis (MDR-TB) treatment and the subsequent development of extensively drug-resistant TB (XDR-TB). The first XDR-TB case in the Western Cape province of South Africa was recorded in 1992, approximately 5 - 7 years after the regional introduction of MDR-TB-like treatment. Between 1990 and 2002 we identified 48 patients with XDR-TB in the Cape Metropole region of the Western Cape province. Patients were predominantly HIV-uninfected and median survival was 10.8 months. XDR-TB has therefore been present in the Western Cape at least since 1992. These data inform public health policy relevant to the introduction of new anti-TB drug regimens.
引用
收藏
页码：636 / +
页数：2
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