Drug Repurposing: An Alternative Strategy to Treat COVID-19

被引：0
|
作者：
Han, Pengyu [1 ,2 ]
Zheng, Huifang [1 ]
Wen, Pingping [3 ]
Pan, Li [3 ]
Geng, Dan [3 ]
Sun, Dianxing [1 ]
机构：
[1] 980th Hosp PLA Joint Logist Force, Dept Infect Dis, Shijiazhuang 050082, Hebei, Peoples R China
[2] Dandong Customs House, Dandong, Peoples R China
[3] Dept Technol, Dalian, Peoples R China
来源：
CURRENT PHARMACEUTICAL BIOTECHNOLOGY | 2022年 / 23卷 / 06期
基金：
中国国家自然科学基金;
关键词：
COVID-19; SARS-CoV-2; immuno-regulation; risk factor; pH; Anti-viral agents; surfactants; PROLIFERATOR-ACTIVATED RECEPTORS; N-ACETYL-CYSTEINE; INSULIN-RESISTANCE; HOST-DEFENSE; ZINC IONS; SARS-COV; T-CELLS; VIRUS; INFLAMMATION; DIETHYLCARBAMAZINE;
D O I：
10.2174/1389201022666210709141320
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In order to curve the ongoing trend of the COVID-19 pandemic and save more lives, effective treatments against COVID-19 are urgently needed. Compared to developing new drugs, which may take too much time, it's more efficient and cost-effective to repurpose existing drugs in the treatment of COVID-19. Fortunately, some of the shared features of COVID-19 and other wellknown diseases make it possible to use old strategies to combat this new challenge. In this paper, we reviewed various possible strategies of drug repurposing in the treatment of COVID-19 and explored the possible scientific mechanisms behind each strategy.
引用
收藏
页码：818 / 827
页数：10
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