Fermentation Biotechnology Microbial production of 1,3-propanediol

被引：1
|
作者：
Steverding, Dietmar [1 ,2 ,3 ]
机构：
[1] Univ E Anglia, Sch Med Hlth Policy & Practice, Biomed Res Ctr, Norwich NR4 7TJ, Norfolk, England
[2] Max Planck Inst Biol, D-7400 Tubingen, Germany
[3] Univ Heidelberg, Inst Hyg, Nachwuchsgrp, D-6900 Heidelberg, Germany
来源：
CHEMIE IN UNSERER ZEIT | 2010年 / 44卷 / 06期
关键词：
GLYCEROL;
D O I：
10.1002/ciuz.201000531
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The microbial production of 1,3-propanediol is a success story for modern biotechnology. Once a specialty chemical, 1,3-propanediol has risen to a bulk chemical within a few years. The interest in 1,3-propanediol as a new commodity chemical is due to its use as a starting material for novel polymers with excellent physical and chemical properties. With the introduction of a new biotechnological production process, 1,3-propanediol can be made at a competitive price from renewable resources with the aid of genetically modified E. coli bacteria. The development of the recombinant E. coli strain took more than 7 years and 36 genes had to be altered in order to enable the production of 1,3-propanediol. In addition, the transformation of glycerol to 1,3-propanediol could be the solution for the gycerol problem of biodiesel production. Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：384 / 389
页数：6
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