Metabolic engineering for the microbial production of 1,3-propanediol

被引：542
|
作者：
Nakamura, CE
Whited, GM
机构：
[1] DuPont Co Inc, Cent Res & Dev, Expt Stn, Wilmington, DE 19880 USA
[2] Genencor Int Inc, Palo Alto, CA 94304 USA
来源：
CURRENT OPINION IN BIOTECHNOLOGY | 2003年 / 14卷 / 05期
关键词：
D O I：
10.1016/j.copbio.2003.08.005
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Improvements in the biological production of 1,3-propanediol, a key component of an emerging polymer business, have been realized. Utilizing genes from natural strains that produce 1,3-propanediol from glycerol, metabolic engineering has enabled the development of a recombinant strain that utilizes the lower cost feedstock D-glucose. This accomplishment bodes well for future metabolic engineering efforts and, ultimately, for increased societal benefit obtained through the production of chemicals from renewable resources.
引用
收藏
页码：454 / 459
页数：6
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