Iridoid glycosides from Phlomis likiangensis with free -radical scavenging activity

被引:5
|
作者
Li, Xiao-Hui
Lu, Li-He
Li, Xu-Hong
Li, Yun-Biao
Zha, Yu-Feng
Fu, De-Huan
Mei, Shuang-Xi [1 ]
Cui, Tao
Wang, Jing-Kun [1 ]
Zhu, Zhao-Yun
机构
[1] Yunnan Inst Mat Med, Kunming 650111, Yunnan, Peoples R China
关键词
Iridoid glycoside; Phlomis likiangensis; Free-radical scavenging activity; DPPH; ABTS; ANTIOXIDANT ACTIVITY; GLUCOSIDES; ROOTS; ABTS;
D O I
10.1016/j.tetlet.2017.10.020
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Phytochemical investigation of an extract of the aerial and underground parts of Phlomis likiangensis resulted in the identification of five new iridoid glycosides, namely as 5,9-epi-6-methoxy-7,8-dehydropenstemonoside (1), 6-methoxy-7,8-dehydropenstemonoside (2), 6-methoxy-7,8-dehydropenstemoside (3), 6-ethoxy-7,8-dehydropenstemoside (4), and phloloside G (5). On the basis of a combination of spectroscopic data and acid hydrolysis, their structures were determined. The free-radical scavenging activity of these compounds was assessed using the DPPH and ABTS assays. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码:4395 / 4399
页数:5
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