Copper-Catalyzed Direct Benzylation or Allylation of 1,3-Azoles with N-Tosylhydrazones

被引：228
|
作者：
Zhao, Xia [1 ]
Wu, Guojiao [1 ]
Zhang, Yan [1 ]
Wang, Jianbo [1 ]
机构：
[1] Peking Univ, BNLMS, Key Lab Bioorgan Chem & Mol Engn, Minist Educ,Coll Chem, Beijing 100871, Peoples R China
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2011年 / 133卷 / 10期
关键词：
C-H BOND; CROSS-COUPLING REACTIONS; MEDIATED DIRECT ARYLATION; DIRECT ALKYNYLATION; HIGHLY EFFICIENT; C-2; ARYLATION; PALLADIUM; ARYL; AZOLES; HETEROCYCLES;
D O I：
10.1021/ja111249p
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Cu-Catalyzed cross-coupling of N-tosylhydrazones with 1,3-azoles leads to the direct C-H benzylation or allylation. Cu carbene migratory insertion is proposed to play the key role in this transformation.
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页码：3296 / 3299
页数：4
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