Fibroblast biology - Development and differentiation of synovial fibroblasts in arthritis

被引：58
|
作者：
Edwards, JCW [1 ]
机构：
[1] UCL Ctr Rheumatol, London W1P 9PG, England
来源：
ARTHRITIS RESEARCH | 2000年 / 2卷 / 05期
关键词：
embryology; hyaluronan; synoviocyte; synovium; vascular cell adhesion molecule-1;
D O I：
10.1186/ar110
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Synovial fibroblasts occur as two phenotypes - intimal and subintimal. The specialised intimal phenotype includes expression of uridine diphosphoglucose dehydrogenase (UDPGD), vascular cell adhesion molecule-1 (VCAM-1) and complement decay-accelerating factor (DAF). These gene products contribute to specialised functions relating to tissue movement and leucocyte traffic.
引用
收藏
页码：344 / 347
页数：4
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