Transition-Metal-Free Synthesis of 2-Arylimidazolones via Cascade Reaction between Arynes and α,α′-Disubstituted α-Isocyanoacetamides

被引：15
|
作者：
Gesu, Alessandro [1 ]
Pozzoli, Claudio [1 ]
Torre, Enza [1 ]
Aprile, Silvio [1 ]
Pirali, Tracey [1 ]
机构：
[1] Univ Piemonte Orientale, Dipartimento Sci Farmaco, Largo Donegani 2, I-28100 Novara, Italy
来源：
ORGANIC LETTERS | 2016年 / 18卷 / 09期
关键词：
STRAIGHTFORWARD ACCESS; 1,3-DIPOLAR CYCLOADDITION; MULTICOMPONENT REACTION; 3-COMPONENT REACTION; ISOCYANIDES; ARYLATION; INSERTION; PHTHALIMIDES; HETEROCYCLES; EFFICIENT;
D O I：
10.1021/acs.orglett.6b00580
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The reaction between arynes and secondary alpha,alpha'-disubstituted alpha-isocyanoacetamides was developed to access 2-arylimidazolones of structural diversity and complexity in a straightforward manner.
引用
收藏
页码：1992 / 1995
页数：4
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