Clinicopathologic change of gastrointestinal stromal tumor after neoadjuvant imatinib followed by surgical resection

被引：1
|
作者：
Kang, Gil Ho [2 ]
Son, Myoung Won [2 ]
Han, Sun Wook [2 ]
Bae, Sang Ho [2 ]
Kim, Sung Yong [2 ]
Kim, Yong Jin [3 ]
Chung, Gui Ae [4 ]
Cho, Gyu Seok [4 ]
Lee, Moon Soo [2 ]
Park, Nae Kyeong [1 ]
机构：
[1] Soonchunhyang Univ, Gumi Hosp, Dept Surg, Coll Med, Gumi 730030, South Korea
[2] Soonchunhyang Univ, Cheonan Hosp, Coll Med, Dept Surg, Cheonan, South Korea
[3] Soonchunhyang Univ, Coll Med, Seoul Hosp, Dept Surg, Seoul, South Korea
[4] Soonchunhyang Univ, Coll Med, Bucheon Hosp, Dept Surg, Puchon, South Korea
来源：
JOURNAL OF THE KOREAN SURGICAL SOCIETY | 2012年 / 82卷 / 02期
关键词：
Gastrointestinal stromal tumors; Imatinib; Neoadjuvant; MANAGEMENT; GIST;
D O I：
10.4174/jkss.2012.82.2.120
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
A 53-year-old woman was diagnosed with gastrointestinal stromal tumor (GIST) of the stomach. Computed tomography (CT) revealed a huge mass (12 cm in diameter), likely to invade pancreas and spleen. In the operation field, the tumor was in an unresectable state. The patient was then started on imatinib therapy for 4 months. On follow-up imaging studies, the tumor almost disappeared. We performed total gastrectomy and splenectomy upon which two small-sized residual tumors were found on microscopy. hi this paper, we describe a case of clinicopathologic change in unresectable GIST after neoadjuvant imatinib mesylate.
引用
收藏
页码：120 / 124
页数：5
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