Tumor suppressor IKZF1 mediates glucocorticoid resistance in B-cell precursor acute lymphoblastic leukemia

被引:53
|
作者
Marke, R. [1 ]
Havinga, J. [1 ]
Cloos, J. [2 ,3 ]
Demkes, M. [1 ]
Poelmans, G. [4 ,5 ,6 ,7 ]
Yuniati, L. [1 ]
Schenau, D. van Ingen [1 ]
Sonneveld, E. [8 ]
Waanders, E. [4 ,5 ]
Pieters, R. [9 ]
Kuiper, R. P. [4 ,5 ]
Hoogerbrugge, P. M. [9 ]
Kaspers, G. J. L. [2 ]
van Leeuwen, F. N. [1 ]
Scheijen, B. [1 ]
机构
[1] Radboud Univ Nijmegen, Med Ctr, Lab Pediat Oncol, Nijmegen, Netherlands
[2] VU Univ Med, Dept Pediat Oncol Hematol, Amsterdam, Netherlands
[3] VU Univ Med, Dept Hematol, Amsterdam, Netherlands
[4] Radboud Univ Nijmegen, Med Ctr, Dept Human Genet, Nijmegen, Netherlands
[5] Radboud Inst Mol Life Sci, Nijmegen, Netherlands
[6] Radboud Univ Nijmegen, Dept Cognit Neurosci, Nijmegen, Netherlands
[7] Radboud Univ Nijmegen, Dept Mol Anim Physiol, Nijmegen, Netherlands
[8] Dutch Childhood Oncol Grp, The Hague, Netherlands
[9] Princess Maxima Ctr Pediat Oncol, Utrecht, Netherlands
关键词
INHIBITION; DELETIONS; REVERSAL;
D O I
10.1038/leu.2015.359
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:1599 / 1603
页数:6
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