Nickel-catalyzed borylation of arenes and indoles via C-H bond cleavage

被引：136
|
作者：
Furukawa, Takayuki [1 ]
Tobisu, Mamoru [1 ,2 ,3 ]
Chatani, Naoto [1 ]
机构：
[1] Osaka Univ, Fac Engn, Dept Appl Chem, Suita, Osaka 5650871, Japan
[2] Osaka Univ, Grad Sch Engn, Ctr Atom & Mol Technol, Suita, Osaka 5650871, Japan
[3] Kyoto Univ, ESICB, Kyoto 6158510, Japan
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 30期
关键词：
SN BONDS; ACTIVATION; FUNCTIONALIZATION; CONSTRUCTION; STANNYLATION; ALKYLATION; ETHERS;
D O I：
10.1039/c5cc01378j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The first nickel-catalyzed method for the borylation of carbon-hydrogen bonds in arenes and indoles is described. The use of an N-heterocyclic carbene ligand is essential for an efficient reaction, with an N-cyclohexyl-substituted derivative being optimal. This method is readily applied to the gram scale synthesis of 2-borylindole.
引用
收藏
页码：6508 / 6511
页数：4
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