Experimental infection of colostrum deprived piglets with porcine circovirus 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) potentiates PCV2 replication

被引：290
|
作者：
Allan, GM
McNeilly, F
Ellis, J
Krakowka, S
Meehan, B
McNair, I
Walker, I
Kennedy, S
机构：
[1] Dept Agr & Rural Dev No Ireland, Dept Virol, Vet Sci Div, Belfast BT4 3SD, Antrim, North Ireland
[2] Univ Saskatchewan, Western Coll Vet Med, Dept Vet Microbiol & Pathol, Saskatoon, SK S7N 0W0, Canada
[3] Ohio State Univ, Coll Vet Med, Dept Vet Biosci, Columbus, OH 43210 USA
来源：
ARCHIVES OF VIROLOGY | 2000年 / 145卷 / 11期
关键词：
D O I：
10.1007/s007050070031
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Experimental infection of colostrum-deprived (CD) pigs with a combined inoculum of porcine circovirus 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) potentiated the replication and distribution of PCV2 virus? when compared with pigs inoculated with PCV2 alone. The replication and distribution of PRRSV in dually infected pigs was not enhanced, when compared to pigs inoculated with PRRSV alone. The mechanisms involved in the potentiation of PCV2 replication in PCV2/PRRSV and PCV2/porcine parvovirus (PPV) dually infected pigs may relate to the fact that monocyte/macrophage cell types are common targets of these 3 viruses.
引用
收藏
页码：2421 / 2429
页数：9
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