Micronucleus test on gas station attendants

被引：0
|
作者：
Benites, Cibelem Iribarrem [1 ]
Amado, Lilian Lund [1 ]
Packeiser Vianna, Rita Aloma [1 ]
Martino-Roth, Maria da Graca [1 ,2 ]
机构：
[1] Univ Fed Pelotas, Dept Zool & Genet, Pelotas, RS, Brazil
[2] Univ Catolica Pelotas, Escola Med, Pelotas, RS, Brazil
来源：
GENETICS AND MOLECULAR RESEARCH | 2006年 / 5卷 / 01期
关键词：
micronucleus test; mutagenicity; occupational exposure; gas station attendants; exfoliated cells; biological monitoring;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In the present study, the micronucleus test was applied in exfoliated cells of buccal mucosa to assess the mutagenicity risk associated with occupational exposure for gas station attendants. For each individual, 2000 exfoliated buccal cells were analyzed for micronucleus frequency. A highly significant difference was found between exposed and control groups. Likewise, a significant difference was found between these groups regarding the frequency of binucleated and broken egg cells. To determine whether smoking, alcohol habit, age, gender, or working time could exert any additional effect, we determined the frequency of micronuclei and binucleated and broken egg cells amongst exposed and control individuals. The results allowed us to conclude that the individuals studied belong to a risk group and should periodically undergo biological monitoring and appropriate care.
引用
收藏
页码：45 / 54
页数：10
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