High concentrations of plasma brain-derived neurotrophic factor in methamphetamine users

被引：81

作者：

Kim, DJ

Roh, S

Kim, Y ^{[1
]}

Yoon, SJ

Lee, HK

Han, CS

Kim, YK ^{[1
]}

机构：

[1] Korea Univ, Coll Med, Dept Psychiat, Seoul 136701, South Korea

[2] Catholic Univ Korea, Korea Univ, Ansan Hosp, Coll Med,Dept Psychiat, Seoul 425020, South Korea

[3] Hanyang Univ, Coll Med, Dept Neuropsychiat, Seoul 133791, South Korea

来源：

NEUROSCIENCE LETTERS | 2005年 / 388卷 / 02期

关键词：

BDNF; methamphetamine; ELISA; dopamine; neurotoxicity;

D O I：

10.1016/j.neulet.2005.06.042

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Methamphetamine is a highly addictive drug that has a neurotoxic effect on the brain. A growing body of evidence suggests that brain-derived neurotrophic factor (BDNF) is associated with addictive behavior. The present study investigated the changes in plasma BDNF concentration that were induced by chronic methamphetamine use. Using an enzyme-linked immunosorbent assay (ELISA), we measured peripheral BDNF levels in methamphetamine users and in a control group. The plasma BDNF concentrations of methamphetamine users were significantly higher compared with those of controls (2536.3 pg/ml versus 1352.6 pg/ml). This finding suggests that BDNF plays some role in the neurotoxicity of methamphetamine. (C) 2005 Elsevier Ireland Ltd. All rights reserved.

引用

页码：112 / 115

页数：4

共 50 条

[1] Plasma brain-derived neurotrophic factor concentrations in children and adolescents
Iughetti, L.
Casarosa, E.
Predieri, B.
Patianna, V.
Luisi, S.
[J]. NEUROPEPTIDES, 2011, 45 (03) : 205 - 211
[2] Decreased plasma concentrations of brain-derived neurotrophic factor in preeclampsia
Perucci, Luiza Oliveira
Marciano Vieira, Erica Leandro
Teixeira, Antonio Lucio
Gomes, Karina Braga
Dusse, Luci Maria
Sousa, Lirlandia Pires
[J]. CLINICA CHIMICA ACTA, 2017, 464 : 142 - 147
[3] Low concentrations of plasma brain-derived neurotrophic factor in patients with panic disorder
Yang, J. C.
Kim, Y. K.
Lee, M. S.
Yoon, J. S.
Eun, S. J.
Cao, H. Z.
[J]. EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2006, 16 : S222 - S222
[4] PLASMA CONCENTRATIONS OF BRAIN-DERIVED NEUROTROPHIC FACTOR IN PATIENTS WITH GENDER IDENTITY DISORDER
Vaitses Fontanari, Anna Martha
Andreazza, Tahiana
Costa, Angelo B.
Koff, Walter J.
Salvador, Jaqueline
Aguiar, Bianca
Ferrari, Pamela
Massuda, Raffael
Pedrini, Mariana
Silveira, Esalba
Belmonte-de-Abreu, Paulo S.
Gama, Clarissa S.
Kapczinski, Flavio
[J]. JOURNAL OF SEXUAL MEDICINE, 2013, 10 : 332 - 332
[5] Brain-derived neurotrophic factor concentrations in tetraplegic athletes
Zeller, S.
Abel, T.
Rojas-Vega, S.
Foitschik, T.
Strueder, H. K.
[J]. SPINAL CORD, 2015, 53 (11) : 791 - 794
[6] Brain-derived neurotrophic factor concentrations in tetraplegic athletes
S Zeller
T Abel
S Rojas-Vega
T Foitschik
H K Strueder
[J]. Spinal Cord, 2015, 53 : 791 - 794
[7] Repeated methamphetamine exposure decreases plasma brain-derived neurotrophic factor levels in rhesus monkeys
Zhang, Wenlei
Zhou, Jiahui
Su, Hang
Zhang, Xiaocheng
Song, Weichen
Wang, Zijing
Tang, Chengjie
Uludag, Kadir
Zhao, Min
Xiong, Zhi-Qi
Zhai, Rongwei
Jiang, Haifeng
[J]. GENERAL PSYCHIATRY, 2023, 36 (05)
[8] Brain-derived neurotrophic factor rescues neuronal death induced by methamphetamine
Matsuzaki, H
Namikawa, K
Kiyama, H
Mori, N
Sato, K
[J]. BIOLOGICAL PSYCHIATRY, 2004, 55 (01) : 52 - 60
[9] Brain-derived neurotrophic factor levels and depression during methamphetamine withdrawal
Ren, Wenwei
Luan, Xiaoqian
Zhang, Jie
Gutteea, Priyanka
Cai, Yan
Zhao, Jiyun
Gu, Yingying
Wu, Chaowen
Su, Hang
Tao, Jingyan
Xie, Ying
Lv, Dezhao
Feng, Liang
He, Jincai
[J]. JOURNAL OF AFFECTIVE DISORDERS, 2017, 221 : 165 - 171
[10] Brain-derived neurotrophic factor in plasma of women with endometriosis
Giannini, Andrea
Bucci, Fiorella
Luisi, Stefano
Cela, Vito
Pluchino, Nicola
Merlini, Sara
Casarosa, Elena
Russo, Marinella
Cubeddu, Alessandra
Daino, Diana
Artini, Paolo G.
Genazzani, Andrea R.
[J]. JOURNAL OF ENDOMETRIOSIS AND PELVIC PAIN DISORDERS, 2010, 2 (03) : 144 - 150

← 1 2 3 4 5 →