Does methotrexate improve TNF inhibitor drug survival in elderly patients with RA?

被引：2
|
作者：
Lahaye, Clement [1 ,2 ]
Soubrier, Martin [3 ]
机构：
[1] Ctr Hosp talier niv Clermont Ferrand, Serv Geriatrie, Clermont Ferrand, France
[2] Univ Clermont Auvergne, Inst Natl Rech Agr Alimentat & Environm, Unite Nutr Humaine, Ctr Rech Nutr Humaine Auvergne, Clermont Ferrand, France
[3] Ctr Hosp Univ Clermont Ferrand, Serv Rhumatol, Clermont Ferrand, France
来源：
NATURE REVIEWS RHEUMATOLOGY | 2020年 / 16卷 / 07期
关键词：
FRAILTY;
D O I：
10.1038/s41584-020-0411-7
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Methotrexate is commonly used in combination with biologic DMARDs in the treatment of rheumatoid arthritis on the basis that the combined therapy has synergistic benefits. New data challenge this concept in the treatment of older adults and highlight the uncertainty of the mode of action of methotrexate in this population.
引用
收藏
页码：353 / 354
页数：2
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