Mechanisms of Toxic Effects of Homocysteine on the Nervous System

被引：3
|
作者：
Nevmerzhytska, N. M. [1 ]
Orzheshkovskyi, V. V. [2 ]
Dzevulska, I. V. [1 ]
Savosko, S. I. [1 ]
机构：
[1] Bogomolets Natl Med Univ, Kiev, Kiev, Ukraine
[2] Shupyk Natl Med Acad PostGrad Educ, Minist Publ Hlth Ukraine, Kiev, Kiev, Ukraine
来源：
NEUROPHYSIOLOGY | 2019年 / 51卷 / 05期
关键词：
homocysteine; hyperhomocysteinemia; toxic effects; pathogenesis; nervous system; CYSTATHIONINE BETA-SYNTHASE; PLASMA TOTAL HOMOCYSTEINE; FOLIC-ACID THERAPY; B-VITAMINS; PARKINSONS-DISEASE; PRIMARY PREVENTION; DNA METHYLATION; ISCHEMIC-STROKE; S-NITROSYLATION; CELL-ACTIVATION;
D O I：
10.1007/s11062-020-09832-x
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
The review describes the metabolism of homocystein, causes of hyperhomocysteinemia, mechanisms underlying the respective negative effects on the nervous system, and main principles of correction of such disorders.
引用
收藏
页码：379 / 387
页数：9
相关论文
共 50 条
  • [1] Mechanisms of Toxic Effects of Homocysteine on the Nervous System
    N. M. Nevmerzhytska
    V. V. Orzheshkovskyi
    I. V. Dzevulska
    S. I. Savosko
    [J]. Neurophysiology, 2019, 51 : 379 - 387
  • [2] The Toxic Effects of Formaldehyde on the Nervous System
    Songur, Ahmet
    Ozen, Oguz Aslan
    Sarsilmaz, Mustafa
    [J]. REVIEWS OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, VOL 203, 2010, 203 : 105 - 118
  • [3] SPECIFIC TOXIC EFFECTS ON THE NERVOUS-SYSTEM
    CREMER, JE
    [J]. GENERAL PHARMACOLOGY, 1981, 12 (02): : A2 - A2
  • [4] Mechanisms of toxic injury in the peripheral nervous system: Neuropathologic considerations
    Jortner, BS
    [J]. TOXICOLOGIC PATHOLOGY, 2000, 28 (01) : 54 - 69
  • [5] TOXIC EFFECTS OF CARBON TETRACHLORIDE ON THE CENTRAL NERVOUS SYSTEM
    STEVENS, H
    FORSTER, FM
    [J]. TRANSACTIONS OF THE AMERICAN NEUROLOGICAL ASSOCIATION, 1953, : 136 - 137
  • [6] Carboplatin toxic effects on the peripheral nervous system of the rat
    Cavaletti, G
    Fabbrica, D
    Minoia, C
    Frattola, L
    Tredici, G
    [J]. ANNALS OF ONCOLOGY, 1998, 9 (04) : 443 - 447
  • [7] Toxic Effects of Glyphosate on the Nervous System: A Systematic Review
    Costas-Ferreira, Carmen
    Duran, Rafael
    Faro, Lilian R. F.
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (09)
  • [8] TOXIC EFFECTS OF CHLORINE GAS ON CENTRAL NERVOUS SYSTEM
    不详
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1946, 132 (05): : 312 - 312
  • [9] Protective effects and mechanisms of sirtuins in the nervous system
    Zhang, Feng
    Wang, Suping
    Gan, Li
    Vosler, Peter S.
    Gao, Yanqin
    Zigmond, Michael J.
    Chen, Jun
    [J]. PROGRESS IN NEUROBIOLOGY, 2011, 95 (03) : 373 - 395
  • [10] Potentially toxic effects of anaesthetics on the developing central nervous system
    Gascon, E.
    Klauser, R.
    Kiss, J. Z.
    Vutskits, L.
    [J]. EUROPEAN JOURNAL OF ANAESTHESIOLOGY, 2007, 24 (03) : 213 - 224
12345