Actin nucleation: Putting the brakes on Arp2/3

被引：4
|
作者：
Qualmann, Britta [1 ]
Kessels, Michael M. [1 ]
机构：
[1] Univ Jena, Inst Biochem 1, D-07743 Jena, Germany
来源：
CURRENT BIOLOGY | 2008年 / 18卷 / 10期
关键词：
D O I：
10.1016/j.cub.2008.04.014
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The Arp2/3 complex is a powerful nucleator of actin filaments when activated. A recent study has now revealed that this complex is not only subject to positive control but that there also exists a brake on its activity. This brake can suppress both the basal activity of the Arp2/3 complex as well as its activation by nucleation-promoting factors.
引用
收藏
页码：R420 / R423
页数：4
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