T cells of patients with myelodysplastic syndrome are frequently derived from the malignant clone

被引：11
|
作者：
Vercauteren, Suzanne M. [1 ,2 ,3 ]
Starczynowski, Daniel T. [2 ,3 ]
Sung, Sandy [2 ,3 ]
McNeil, Kelly [4 ]
Salski, Chris [4 ]
Jensen, Clara-Lynn [5 ]
Bruyere, Helene [3 ,5 ]
Lam, Wan L. [3 ,6 ]
Karsan, Aly [2 ,3 ,4 ]
机构：
[1] British Columbia Childrens Hosp, Pathol & Lab Med, Vancouver, BC V6H 3V4, Canada
[2] BC Canc Agcy, British Columbia Genome Sci Ctr, Vancouver, BC, Canada
[3] Univ British Columbia, Pathol & Lab Med, Vancouver, BC V5Z 1M9, Canada
[4] BC Canc Agcy, Canc Genet Lab, Vancouver, BC, Canada
[5] Vancouver Gen Hosp, Pathol & Lab Med, Vancouver, BC, Canada
[6] British Columbia Canc Agcy, Integrated Oncol Program, Vancouver, BC V5Z 4E6, Canada
来源：
BRITISH JOURNAL OF HAEMATOLOGY | 2012年 / 156卷 / 03期
关键词：
myelodysplastic syndrome; T cell clonality; array; karyotype; ARRAY CGH ANALYSIS; MONOSOMY-7; RESOLUTION; LEUKEMIA; GENE;
D O I：
10.1111/j.1365-2141.2011.08872.x
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：409 / 412
页数：4
相关论文
共 50 条
  • [21] The stromal component of the marrow microenvironment is not derived from the malignant clone in MDS
    Ramakrishnan, Aravind
    Awaya, Norihiro
    Bryant, Eileen
    Tbrok-Storb, Beverly
    BLOOD, 2006, 108 (02) : 772 - 773
  • [22] In Vitro Deprivation of CD8+CD57+t Cells Promotes the Malignant Growth of Bone Marrow Stem/Progenitor Cells in Patients with Myelodysplastic Syndrome
    Zhang, Qianqiao
    Li, Xiao
    Zhang, Zheng
    Xu, Feng
    He, Qi
    Wu, Lingyun
    Chang, Chunkang
    BLOOD, 2009, 114 (22) : 701 - 701
  • [23] Identification of CD39 as a Marker for the Circulating Malignant T-Cell Clone of Sezary Syndrome Patients
    Bensussan, Armand
    Janela, Baptiste
    Thonnart, Nicolas
    Bagot, Martine
    Musette, Philippe
    Ginhoux, Florent
    Marie-Cardine, Anne
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2019, 139 (03) : 725 - 728
  • [24] Circulating T Cells Derived From Patients with Low Risk Myelodysplastic Syndromes Show Altered Chemokine Receptor Expression
    Sand, Kristoffer E.
    Kittang, Astrid Olsnes
    Bruserud, Oystein
    BLOOD, 2010, 116 (21) : 1637 - 1638
  • [25] Apoptotic cells and clonally expanded cytotoxic T cells in bone marrow trephines of patients with myelodysplastic syndrome
    Puelhorn, Heinke
    Herrmann, Martin
    Harms, Harry
    Jung, Andreas
    Baumann, Irith
    HISTOPATHOLOGY, 2012, 61 (02) : 200 - 211
  • [26] Lenalidomide up-regulates SPARC and inhibits in vitro growth of the malignant clone in myelodysplastic syndrome patients with 5q deletion.
    Pellagatti, Andrea
    Jadersten, Martin
    Forsblom, Ann-Mari
    Cattan, Helen
    Christensson, Birger
    Emanuelsson, Emma K.
    Merup, Mats
    Nilsson, Lars
    Samuelsson, Jan
    Sander, Birgitta
    Wainscoat, James S.
    Boultwood, Jacqueline
    Hellstrom-Lindberg, Eva
    BLOOD, 2006, 108 (11) : 256A - 257A
  • [27] Tracking the MDS clone in peripheral blood (PB) cells from patients (pts) with Myelodysplastic syndrome (MDS) undergoing Azacitidine (AZAC)-based therapy.
    Cozza, Amanda
    Silverman, Lewis
    Odchimar-Reissig, Rosalie
    Schulman, Ilene
    Zinzar, Svetlana
    Najfeld, Vesna
    BLOOD, 2007, 110 (11) : 222B - 222B
  • [28] Cytokine regulation of the growth of clonal malignant T-cells from patients with Sezary Syndrome.
    Fox, FE
    Niu, ZT
    Lessin, S
    Rook, AH
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1997, 108 (04) : 86 - 86
  • [29] LEUKOCYTE-DERIVED INHIBITORY ACTIVITY IN PATIENTS WITH MYELODYSPLASTIC SYNDROME
    CUKROVA, V
    NEUWIRTOVA, R
    CERMAK, J
    MALASKOVA, V
    NEUWIRT, J
    BLUT, 1987, 55 (03): : 165 - 171
  • [30] Functional characterization of adult mesenchymal stromal cells from patients with myelodysplastic syndrome
    Boxberger, S.
    Bornhaeuser, M.
    Mohr, B.
    von Bonin, M.
    Ehninger, G.
    Platzbecker, U.
    LEUKEMIA RESEARCH, 2007, 31 : S51 - S52
12345