LUMILIXIMAB MODULATES PI3-K/AKT PATHWAY AND INDUCES APOPTOSIS IN CLL CELLS

被引:0
|
作者
Shehata, M. [1 ]
Schnabl, S. [1 ]
Ponath, E. [1 ]
Demirtas, D. [1 ]
Hilgarth, M. [1 ]
Badrnya, S. [1 ]
Tauber, S. [1 ]
Bilban, M. [1 ]
Eigenberger, K. [1 ]
Schwarzmeier, J. [1 ]
Gaiger, A. [1 ]
Hubmann, R. [1 ]
Zielinski, C. [1 ]
Hughes, S. [2 ]
Maclaren, A. [2 ]
Jaeger, U. [1 ]
机构
[1] Med Univ Vienna, Vienna, Austria
[2] Biogen Idec Inc, Maidenhead, Berks, England
来源
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
0117
引用
收藏
页码:47 / 47
页数:1
相关论文
共 50 条
  • [21] Dimethoxytolyl propylresorcinol induces apoptosis and mitophagy in human leukemia cells through the PI3K/AKT pathway
    Wei, Jianming
    Zhong, Xiaojuan
    Peng, Huiting
    Cui, Bingqing
    Yue, Xianlin
    Sun, Zewei
    Shi, Jing
    JOURNAL OF CANCER, 2024, 15 (01): : 103 - 112
  • [22] Triptolide suppresses the proliferation and induces the apoptosis of nasopharyngeal carcinoma cells via the PI3K/Akt pathway
    Wang, Mi
    Chen, Bo
    Chai, Liang
    ONCOLOGY LETTERS, 2019, 17 (01) : 1372 - 1378
  • [23] Didymin Inhibits Proliferation and Induces Apoptosis in Gastric Cancer Cells by Modulating the PI3K/Akt Pathway
    Zhang, Tong
    Xu, Bin
    NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL, 2025,
  • [24] Grifolin induces apoptosis via inhibition of PI3K/AKT signalling pathway in human osteosarcoma cells
    Song Jin
    Rui-Ping Pang
    Jing-Nan Shen
    Gang Huang
    Jin Wang
    Jia-Guo Zhou
    Apoptosis, 2007, 12 : 1317 - 1326
  • [25] Thioridazine induces apoptosis by targeting the PI3K/Akt/mTOR pathway in cervical and endometrial cancer cells
    Kang, Sokbom
    Dong, Seung Myung
    Kim, Boh-Ram
    Park, Mi Sun
    Trink, Barry
    Byun, Hyun-Jung
    Rho, Seung Bae
    APOPTOSIS, 2012, 17 (09) : 989 - 997
  • [26] Thioridazine induces apoptosis by targeting the PI3K/Akt/mTOR pathway in cervical and endometrial cancer cells
    Sokbom Kang
    Seung Myung Dong
    Boh-Ram Kim
    Mi Sun Park
    Barry Trink
    Hyun-Jung Byun
    Seung Bae Rho
    Apoptosis, 2012, 17 : 989 - 997
  • [27] Herbacetin induces apoptosis in HepG2 cells: Involvements of ROS and PI3K/Akt pathway
    Qiao, Yan
    Xiang, Qisen
    Yuan, Li
    Xu, Li
    Liu, Zhigang
    Liu, Xuebo
    FOOD AND CHEMICAL TOXICOLOGY, 2013, 51 : 426 - 433
  • [28] Downregulation of PI3-K/Akt/PTEN pathway and activation of mitochondrial intrinsic apoptosis by Diclofenac and Curcumin in colon cancer
    Rana, Chandan
    Piplani, Honit
    Vaish, Vivek
    Nehru, Bimla
    Sanyal, S. N.
    MOLECULAR AND CELLULAR BIOCHEMISTRY, 2015, 402 (1-2) : 225 - 241
  • [29] Involvement of the PI3-K/Akt survival pathway in the regulation of apoptosis during estrous cycle in the rat endometrium.
    Dery, MC
    Shooner, C
    Parent, S
    Asselin, E
    BIOLOGY OF REPRODUCTION, 2002, 66 : 320 - 321
  • [30] Downregulation of PI3-K/Akt/PTEN pathway and activation of mitochondrial intrinsic apoptosis by Diclofenac and Curcumin in colon cancer
    Chandan Rana
    Honit Piplani
    Vivek Vaish
    Bimla Nehru
    S. N. Sanyal
    Molecular and Cellular Biochemistry, 2015, 402 : 225 - 241