Baricitinib in Patients with Systemic Lupus Erythematosus: Results from a Phase 2, Randomized, Double-Blind, Placebo-Controlled Study

被引:0
|
作者
Wallace, Daniel J. [1 ]
Furie, Richard [2 ]
Tanaka, Yoshiya [3 ]
Kalunian, Kenneth C. [4 ]
Mosca, Marta [5 ]
Petri, Michelle [6 ]
Dorner, Thomas [7 ,8 ]
Cardiel, Mario H. [9 ]
Bruce, Ian N. [10 ]
Gomez, Elisa [11 ]
DeLozier, Amy M. [11 ]
Janes, Jonathan [11 ]
Linnik, Matthew D. [11 ]
de Bono, Stephanie [11 ]
Silk, Maria E. [11 ]
Hoffman, Robert W. [11 ]
机构
[1] Univ Calif Los Angeles, David Geffen Sch Med, Cedars Sinai Med Ctr, Los Angeles, CA 90095 USA
[2] Zucker Sch Med Hofstra Northwell, Div Rheumatol, Great Neck, NY USA
[3] Univ Occupat & Environm Hlth, Kitakyushu, Fukuoka, Japan
[4] Univ Calif San Diego, Sch Med, La Jolla, CA 92093 USA
[5] Univ Pisa, Pisa, Italy
[6] Johns Hopkins Univ, Sch Med, Med Rheumatol, Baltimore, MD USA
[7] Charite Univ Med Berlin, Berlin, Germany
[8] Deutsch Rheumaforschungszentrum DRFZ, Berlin, Germany
[9] Ctr Invest Clin Morelia SC, Morelia, Michoacan, Mexico
[10] Univ Manchester, Div Musculoskeletal & Dermatol Sci, Ctr Musculoskeletal Res, Manchester, Lancs, England
[11] Eli Lilly & Co, Indianapolis, IN 46285 USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
970
引用
收藏
页数:2
相关论文
共 50 条
  • [41] Phase I, Randomized, Double-Blind, Placebo-Controlled, Multiple Intravenous, Dose-Ascending Study of Sirukumab in Cutaneous or Systemic Lupus Erythematosus
    Szepietowski, Jacek C.
    Nilganuwong, Surasak
    Wozniacka, Anna
    Kuhn, Annegret
    Nyberg, Filippa
    van Vollenhoven, Ronald F.
    Bengtsson, Anders A.
    Reich, Adam
    de Vries, Dick E.
    van Hartingsveldt, Bart
    Robinson, Donald W., Jr.
    Gordon, Robert
    Hsu, Benjamin
    ARTHRITIS AND RHEUMATISM, 2013, 65 (10): : 2661 - 2671
  • [42] A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Multiple, Intravenous, Ascending-Dose Study of Sirukumab in Patients with Cutaneous or Systemic Lupus Erythematosus.
    Szepietowski, Jacek C.
    Nilganuwong, Surasak
    Wozniacka, Anna
    Kuhn, Annegret
    Nyberg, Filippa
    Szechinski, Jacek
    van Vollenhoven, Ronald F.
    Bengtsson, Anders
    Reich, Adam
    de Vries, Dick
    van Hartingsveldt, Bart
    Zhou, Bei
    Hsu, Benjamin
    ARTHRITIS AND RHEUMATISM, 2011, 63 (10): : S496 - S497
  • [43] BIIB059 Demonstrates Improvement in Joint Manifestations in Participants with Systemic Lupus Erythematosus in Part a of a Phase 2, Randomized, Double-Blind, Placebo-Controlled Study
    van Vollenhoven, Ronald
    Furie, Richard
    Kalunian, Kenneth
    Dall'Era, Maria
    Werth, Victoria
    Huang, Xiaobi
    Carroll, Hua
    Musselli, Cristina
    Barbey, Catherine
    Franchimont, Nathalie
    ARTHRITIS & RHEUMATOLOGY, 2021, 73 : 3643 - 3644
  • [44] A PHASE 2, RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND, ASCENDING DOSE STUDY TO EVALUATE EFFICACY, SAFETY, AND TOLERABILITY OF CC 220 IN SUBJECTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
    Furie, R.
    Werth, V. P.
    Lee, E.
    Box, E.
    Fondal, M.
    Kivitz, A.
    Chatham, W. W.
    Kalunian, K. C.
    Legerton, C.
    Anolik, J. H.
    Korish, S.
    Hough, D. R.
    Weiswasser, M.
    Choi, S.
    Schafer, P.
    CLINICAL AND EXPERIMENTAL RHEUMATOLOGY, 2016, 34 (04) : S77 - S77
  • [45] Changes in Gut Microbiota and Systemic Inflammation after Synbiotic Supplementation in Patients with Systemic Lupus Erythematosus: A Randomized, Double-Blind, Placebo-Controlled Trial
    Widhani, Alvina
    Djauzi, Samsuridjal
    Suyatna, Franciscus Dhyanagiri
    Dewi, Beti Ernawati
    CELLS, 2022, 11 (21)
  • [46] Efficacy and Safety of Deucravacitinib, an Oral, Selective, Allosteric TYK2 Inhibitor, in Patients with Active Systemic Lupus Erythematosus: A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study
    Pike, Marilyn
    Merrill, Joan
    Morand, Eric
    van Vollenhoven, Ronald
    Werth, Victoria
    Hobar, Coburn
    Delev, Nikolay
    Shah, Vaishali
    Sharkey, Brian
    Wegman, Thomas
    Catlett, Ian M.
    Banerjee, Subhashis
    Singhal, Shalabh
    ARTHRITIS & RHEUMATOLOGY, 2022, 74 : 2219 - 2221
  • [47] EFFICACY AND SAFETY OF DEUCRAVACITINIB, AN ORAL, SELECTIVE, ALLOSTERIC TYK2 INHIBITOR, IN PATIENTS WITH ACTIVE SYSTEMIC LUPUS ERYTHEMATOSUS: A PHASE 2, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY
    Morand, E.
    Pike, M.
    Merrill, J. T.
    Van Vollenhoven, R.
    Werth, V. P.
    Hobar, C.
    Delev, N.
    Shah, V.
    Sharkey, B.
    Wegman, T.
    Catlett, I.
    Banerjee, S.
    Singhal, S.
    ANNALS OF THE RHEUMATIC DISEASES, 2022, 81 : 209 - 209
  • [48] Efficacy and safety of epratuzumab in patients with moderate/severe active systemic lupus erythematosus: results from EMBLEM, a phase IIb, randomised, double-blind, placebo-controlled, multicentre study
    Wallace, Daniel J.
    Kalunian, Kenneth
    Petri, Michelle A.
    Strand, Vibeke
    Houssiau, Frederic A.
    Pike, Marilyn
    Kilgallen, Brian
    Bongardt, Sabine
    Barry, Anna
    Kelley, Lexy
    Gordon, Caroline
    ANNALS OF THE RHEUMATIC DISEASES, 2014, 73 (01) : 183 - 190
  • [49] Randomized, Double-Blind, Placebo-Controlled Trial of the Effect of Vitamin D3 on the Interferon Signature in Patients With Systemic Lupus Erythematosus
    Aranow, Cynthia
    Kamen, Diane L.
    Dall'Era, Maria
    Massarotti, Elena M.
    Mackay, Meggan C.
    Koumpouras, Fotios
    Coca, Andreea
    Chatham, W. Winn
    Clowse, Megan E. B.
    Criscione-Schreiber, Lisa G.
    Callahan, Sherri
    Goldmuntz, Ellen A.
    Keyes-Elstein, Lynette
    Oswald, Michaela
    Gregersen, Peter K.
    Diamond, Betty
    ARTHRITIS & RHEUMATOLOGY, 2015, 67 (07) : 1848 - 1857
  • [50] Efficacy and Safety of Subcutaneous Belimumab in Systemic Lupus Erythematosus A Fifty-Two-Week Randomized, Double-Blind, Placebo-Controlled Study
    Stohl, William
    Schwarting, Andreas
    Okada, Masato
    Scheinberg, Morton
    Doria, Andrea
    Hammer, Anne E.
    Kleoudis, Christi
    Groark, James
    Bass, Damon
    Fox, Norma Lynn
    Roth, David
    Gordon, David
    ARTHRITIS & RHEUMATOLOGY, 2017, 69 (05) : 1016 - 1027