Design, synthesis, and biological evaluation of novel diazide-containing pyrazole- and isoxazole-based HDAC probes

被引：0
|
作者：
Neelarapu, Raghupathi
Holze, Denise
Velaparthi, Subhash
Bai, He
Brunsteiner, Michael
Blond, Sylvie Y.
Petukhov, Pavel A.
机构：
[1] UIC, Dept Med Chem & Pharmacognosy, Chicago, IL USA
[2] UIC, Ctr Pharmaceut Biotechnol, Chicago, IL USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2011年 / 241卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
329-MEDI
引用
收藏
页数：1
相关论文
共 50 条
  • [41] Design, synthesis and biological evaluation of urea-based benzamides derivatives as HDAC inhibitors
    Yong Zhu
    Xin Chen
    Ting Ran
    Jiaqi Niu
    Shuang Zhao
    Tao Lu
    Weifang Tang
    Medicinal Chemistry Research, 2017, 26 : 2879 - 2888
  • [42] Design, synthesis and biological evaluation of urea-based benzamides derivatives as HDAC inhibitors
    Zhu, Yong
    Chen, Xin
    Ran, Ting
    Niu, Jiaqi
    Zhao, Shuang
    Lu, Tao
    Tang, Weifang
    MEDICINAL CHEMISTRY RESEARCH, 2017, 26 (11) : 2879 - 2888
  • [43] Design, synthesis and biological evaluation of novel HDAC inhibitors with improved pharmacokinetic profile in breast cancer
    Yao, Dahong
    Li, Chenyang
    Jiang, Jin
    Huang, Jian
    Wang, Jinhui
    He, Zhendan
    Zhang, Jin
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 205
  • [44] Design, synthesis, and biological evaluation of novel amide and hydrazide based thioether analogs targeting Histone deacteylase (HDAC) enzymes
    Farag, Ayman B.
    Ewida, Heba A.
    Ahmed, Mahmoud Salama
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 148 : 73 - 85
  • [45] Design, synthesis and biological evaluation of thienopyrimidine hydroxamic acid based derivatives as structurally novel histone deacetylase (HDAC) inhibitors
    Wang, Jiang
    Su, Mingbo
    Li, Tingting
    Gao, Anhui
    Yang, Wei
    Sheng, Li
    Zang, Yi
    Li, Jia
    Liu, Hong
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 128 : 293 - 299
  • [46] Design, synthesis and biological activity evaluation of novel imidazo[5,1-b]thiazole derivatives containing a pyrazole ring based on the intermediate derivatization method
    Li, Meng
    Liu, Shixuan
    Qi, Lei
    Wang, Dandan
    Chang, Xihao
    Lv, Xianhai
    PEST MANAGEMENT SCIENCE, 2025,
  • [47] Design, synthesis and biological evaluation of novel selective thiol-based histone deacetylase(HDAC) VI inhibitors bearing indeno[1,2-c]pyrazole or benzoindazole scaffold
    Qihao Xu
    Shujia Yu
    Yijun Cai
    Jinyu Yang
    Linxiang Zhao
    Dan Liu
    Chemical Research in Chinese Universities, 2018, 34 : 75 - 83
  • [48] Design, Synthesis and Biological Evaluation of Novel Selective Thiol-based Histone Deacetylase(HDAC) VI Inhibitors Bearing Indeno[1,2-c]pyrazole or Benzoindazole Scaffold
    Xu Qihao
    Yu Shujia
    Cai Yijun
    Yang Jinyu
    Zhao Linxiang
    Liu Dan
    CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2018, 34 (01) : 75 - 83
  • [49] Design, synthesis and biological evaluation of a series of CNS penetrant HDAC inhibitors structurally derived from amyloid-β probes
    Myeong A Choi
    Sun You Park
    Hye Yun Chae
    Yoojin Song
    Chiranjeev Sharma
    Young Ho Seo
    Scientific Reports, 9
  • [50] Design, synthesis and biological evaluation of a series of CNS penetrant HDAC inhibitors structurally derived from amyloid-β probes
    Choi, Myeong A.
    Park, Sun You
    Chae, Hye Yun
    Song, Yoojin
    Sharma, Chiranjeev
    Seo, Young Ho
    SCIENTIFIC REPORTS, 2019, 9 (1)
12345