Treatment of Psychogenic Polydipsia With Acetazolamide: A Report of 5 Cases

被引：5

作者：

Takagi, Shunsuke ^{[1
]}

Watanabe, Yutaka ^{[1
]}

Imaoka, Takefumi ^{[1
]}

Sakata, Masuhiro ^{[1
]}

Watanabe, Masako ^{[1
]}

机构：

[1] Natl Ctr Neurol & Psychiat, Dept Psychiat, Kodaira, Tokyo 1878553, Japan

来源：

CLINICAL NEUROPHARMACOLOGY | 2011年 / 34卷 / 01期

关键词：

psychogenic polydipsia; schizophrenia; acetazolamide; water intoxication; hyponatremia; INDUCED WATER-INTOXICATION; SCHIZOPHRENIC-PATIENTS; HYPONATREMIA SYNDROME; PSYCHIATRIC-PATIENTS; DRINKING BEHAVIOR; CAPTOPRIL; CLOZAPINE; RISPERIDONE; PSYCHOSIS;

D O I：

10.1097/WNF.0b013e318205070b

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objective: Psychogenic polydipsia occurs frequently in patients with chronic psychiatric illness and is often unmanageable. We herein report 5 patients in whom acetazolamide was trialed for this symptom. Methods: We encountered a case in which polydipsia improved with incidental administration of acetazolamide. We then used this treatment for 4 additional cases of treatment-resistant psychogenic polydipsia, some of which were accompanied by hyponatremia. Results: Acetazolamide improved polydipsia and/or hyponatremia in 4 of the 5 cases. This treatment was well tolerated and allowed 3 of the patients to permanently leave isolation. Conclusion: Acetazolamide appears to have a beneficial effect in psychogenic polydipsia.

引用

页码：5 / 7

页数：3

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