Targeting Tumor Hypoxia With Hypoxia-Activated Prodrugs

被引:41
|
作者
Yeh, Jen Jen [1 ]
Kim, William Y. [1 ]
机构
[1] Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC 27599 USA
关键词
PHASE-III TRIAL; PANCREATIC-CANCER; SOLID TUMORS; ANTITUMOR-ACTIVITY; CELL CARCINOMA; ONCOLOGY-GROUP; THERAPY; DOXORUBICIN; BREAST; ADENOCARCINOMA;
D O I
10.1200/JCO.2014.60.0759
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
[No abstract available]
引用
收藏
页码:1505 / 1508
页数:4
相关论文
共 50 条
  • [1] Targeting Hypoxia: Hypoxia-Activated Prodrugs in Cancer Therapy
    Li, Yue
    Zhao, Long
    Li, Xiao-Feng
    FRONTIERS IN ONCOLOGY, 2021, 11
  • [2] Targeting the hypoxic fraction of tumours using hypoxia-activated prodrugs
    Phillips, Roger M.
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2016, 77 (03) : 441 - 457
  • [3] Targeting the hypoxic fraction of tumours using hypoxia-activated prodrugs
    Roger M. Phillips
    Cancer Chemotherapy and Pharmacology, 2016, 77 : 441 - 457
  • [4] Hypoxia-Activated Prodrugs of PERK Inhibitors
    Liew, Lydia P.
    Singleton, Dean C.
    Wong, Way W.
    Cheng, Gary J.
    Jamieson, Stephen M. F.
    Hay, Michael P.
    CHEMISTRY-AN ASIAN JOURNAL, 2019, 14 (08) : 1238 - 1248
  • [5] Hypoxia-activated prodrugs forge ahead in cancer
    Jim Kling
    Nature Biotechnology, 2012, 30 : 381 - 381
  • [6] Nitroaromatic Hypoxia-Activated Prodrugs for Cancer Therapy
    Denny, William A.
    PHARMACEUTICALS, 2022, 15 (02)
  • [7] Hypoxia-activated prodrugs forge ahead in cancer
    Kling, Jim
    NATURE BIOTECHNOLOGY, 2012, 30 (05) : 381 - 381
  • [8] Selectively Targeting Tumor Hypoxia With the Hypoxia-Activated Prodrug CP-506
    van der Wiel, Alexander M. A.
    Jackson-Patel, Victoria
    Niemans, Raymon
    Yaromina, Ala
    Liu, Emily
    Marcus, Damienne
    Mowday, Alexandra M.
    Lieuwes, Natasja G.
    Biemans, Rianne
    Lin, Xiaojing
    Fu, Zhe
    Kumara, Sisira
    Jochems, Arthur
    Ashoorzadeh, Amir
    Anderson, Robert F.
    Hicks, Kevin O.
    Bull, Matthew R.
    Abbattista, Maria R.
    Guise, Christopher P.
    Deschoemaeker, Sofie
    Thiolloy, Sophie
    Heyerick, Arne
    Solivio, Morwena J.
    Balbo, Silvia
    Smaill, Jeff B.
    Theys, Jan
    Dubois, Ludwig J.
    Patterson, Adam, V
    Lambin, Philippe
    MOLECULAR CANCER THERAPEUTICS, 2021, 20 (12) : 2372 - 2383
  • [9] Hypoxia-activated prodrugs of the KDAC inhibitor panobinostat
    Calder, Ewen
    Mistry, Ishna
    Hammond, Ester
    Conway, Stuart
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 256
  • [10] In vitro radiosensitization of breast cancer with hypoxia-activated prodrugs
    Aiyappa-Maudsley, Radhika
    Elsalem, Lina
    Ibrahim, Ali I. M.
    Pors, Klaus
    Martin, Stewart G.
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2022, 26 (16) : 4577 - 4590