Photoredox-Catalyzed Deoxygenative Intramolecular Acylation of Biarylcarboxylic Acids: Access to Fluorenones

被引：34

作者：

Ruzi, Rehanguli ^{[1
,2
]}

Zhang, Muliang ^{[2
]}

Ablajan, Keyume ^{[1
]}

Zhu, Chengjian ^{[2
]}

机构：

[1] Xinjiang Univ, Minist Educ & Xinjiang Uygur Autonomous Reg, Key Lab Oil & Gas Fine Chem, Coll Chem & Chem Engn, Urumqi 830046, Peoples R China

[2] Nanjing Univ, Sch Chem & Chem Engn, Jiangsu Key Lab Adv Organ Mat, State Key Lab Coordinat Chem, Nanjing 210023, Jiangsu, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 82卷 / 23期

基金：

中国国家自然科学基金;

关键词：

AROMATIC CARBOXYLIC-ACIDS; ARYLBORONIC ACIDS; DERIVATIVES; FUNCTIONALIZATION; FLUOREN-9-ONES; CYCLIZATION; METALATION; ARYLATION; OXIDATION; RADICALS;

D O I：

10.1021/acs.joc.7b02197

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient deoxygenative radical cyclization reaction has been reported for the synthesis of fluorenones by employing various biarylcarboxylic acids via photoredox catalysis. Attractive features of this process include generation of acyl radical, which quickly underdone intramolecular radical cyclization. This method marks the first photo catalytic intramolecular acyl radical coupling for constructing carbon-carbon bond, which further synthesizes the valuable fluorenone products with mild conditions, good yields, and good functional-group compatibility.

引用

页码：12834 / 12839

页数：6

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