Effects of different intensity of exercise on tissue injury and gene expression in obese rats

被引：0
|
作者：
Wu, Shujia [1 ]
Zhang, Cheng [1 ]
Xu, Feng [2 ]
Li, Ke [2 ]
Li, Anke [1 ]
Wu, Junzhu [1 ]
机构：
[1] Wuhan Univ, Dept Biochem & Mol Biol, Sch Basic Med Sci, 185 Donghu Rd, Wuhan 430072, Hubei, Peoples R China
[2] Wuhan Univ, Sch Basic Med Sci, Ctr Expt Teaching Basic Med Sci, Wuhan 430072, Peoples R China
来源：
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY | 2021年 / 14卷 / 01期
基金：
中国国家自然科学基金;
关键词：
High fat diet-fed model; weight loss; injury; exercise prescription; PERFORMANCE; MOUSE;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Weight loss is an important aspect of chronic disease prevention and management, with increasing rates of overweight and obesity worldwide. Drugs and surgery are popular approaches to lose weight. Given their potential harm to the body, exercise is an alternative widely accepted approach. However, participation in high intensity exercise entails an inherent risk of sports-related injuries. In this study, a rat model fed with high fat diet was employed to investigate the effects of different intensity of exercise prescription on both weight loss and tissue injury after exercise and to find a proper exercise prescription for losing weight with minimal tissues injuries. We inferred that 3% weight bearing might be the proper exercise prescription for high fat diet-fed rats in our experimental setting.
引用
收藏
页码：705 / 712
页数：8
相关论文
共 50 条
  • [41] Effects of exercise training on cardiac apoptosis in obese rats
    Lee, S. -D.
    Shyu, W. -C.
    Cheng, I. -S.
    Kuo, C. -H.
    Chan, Y. -S.
    Lin, Y. -M.
    Tasi, C. -Y.
    Tsai, C. -H.
    Ho, T. -J.
    Huang, C. -Y.
    NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, 2013, 23 (06) : 566 - 573
  • [42] Effects of Exercise Training on Inflammatory and Hypoxic Gene Expression in White Adipose Tissue
    Linden, Melissa A.
    Pincu, Yair
    Martin, Stephen A.
    Woods, Jeffrey A.
    Baynard, Tracy
    MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 2012, 44 : 823 - 823
  • [43] Mitochondrial gene expression in elite cyclists: effects of high-intensity interval exercise
    Niklas, Psilander
    Li, Wang
    Jens, Westergren
    Michail, Tonkonogi
    Kent, Sahlin
    EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, 2010, 110 (03) : 597 - 606
  • [44] Mitochondrial gene expression in elite cyclists: effects of high-intensity interval exercise
    Psilander Niklas
    Wang Li
    Westergren Jens
    Tonkonogi Michail
    Sahlin Kent
    European Journal of Applied Physiology, 2010, 110 : 597 - 606
  • [45] Exercise-induced differential changes in gene expression among arterioles of skeletal muscles of obese rats
    Laughlin, M. Harold
    Padilla, Jaume
    Jenkins, Nathan T.
    Thorne, Pamela K.
    Martin, Jeffrey S.
    Rector, R. Scott
    Akter, Sadia
    Davis, J. Wade
    JOURNAL OF APPLIED PHYSIOLOGY, 2015, 119 (06) : 583 - 603
  • [46] Merit of physical exercise to reverse the higher gene expression of hepatic phosphoenolpyruvate carboxykinase in obese Zucker rats
    Chang, Shih-Pei
    Chen, Yu-Hsuan
    Chang, Weng-Cheng
    Liu, I-Min
    Cheng, Juei-Tang
    LIFE SCIENCES, 2006, 79 (03) : 240 - 246
  • [47] The effects of polyphenol supplementation on adipose tissue morphology and gene expression in overweight and obese humans
    Most, Jasper
    Warnke, Ines
    Boekschoten, Mark V.
    Jocken, Johan W. E.
    de Groot, Philip
    Friedel, Angelika
    Bendik, Igor
    Goossens, Gijs H.
    Blaak, Ellen E.
    ADIPOCYTE, 2018, 7 (03) : 190 - 196
  • [48] Gene expression of angiotensinogen in adipose tissue of obese patients
    G Giacchetti
    E Faloia
    C Sardu
    MA Camilloni
    B Mariniello
    C Gatti
    GGM Garrapa
    M Guerrieri
    F Mantero
    International Journal of Obesity, 2000, 24 : S142 - S143
  • [49] Gene expression of angiotensinogen in adipose tissue of obese patients
    Giacchetti, G
    Faloia, E
    Sardu, C
    Camilloni, MA
    Mariniello, B
    Gatti, C
    Garrapa, GGM
    Guerrieri, M
    Mantero, F
    INTERNATIONAL JOURNAL OF OBESITY, 2000, 24 (Suppl 2) : S142 - S143
  • [50] Acute Exercise Effects On Cardiac Gene Expression In Physically Active And Inactive Rats
    Alessio, Helaine M.
    Simonsen, Michelle L.
    Levine, Kayla
    Taylor, Megan
    White, Peter
    Newsome, David L.
    Hagerman, Ann E.
    JOURNAL OF GENERAL INTERNAL MEDICINE, 2012, 27 : 579 - 579
12345