Study of the photophysical properties of a water-soluble photosensitizer of porphyrin nature-dimegin

A study has been carried out to compare the photophysical properties of a water-soluble photosensitizer of porphyrin nature (dimegin) with photosensitizers currently used in medical practice (photoditazin and radachlorin). Results are given for an investigation of the singlet-oxygen generation efficiency by the photosensitizers when they are irradiated by an LED array (radiation wavelength 395-405 nm). The luminescence spectra of the photosensitizers irradiated by an LED (wavelength 465 nm) were investigated, and it is pointed out that dimegin has higher luminescence intensity than photoditazin and radachlorin. A study was carried out of how the block copolymer Pluronic F-127 in a complex with dimegin affects the capability of the latter to generate singlet oxygen. (C) 2016 Optical Society of America.