Application of 2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate (TBTU) for the synthesis of acid azides

被引：0
|
作者：
Naik, Shankar A. [1 ]
Lalithamba, H. S. [1 ]
Sureshbabu, Vommina V. [1 ]
机构：
[1] Bangalore Univ, Peptide Res Lab, Dept Studies Chem, Bangalore 560001, Karnataka, India
来源：
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2011年 / 50卷 / 01期
关键词：
Acid chlorides; acyl azides; peptide coupling agent; TBTU; AMINO-ACIDS; ACYL AZIDES; EFFICIENT SYNTHESIS; PEPTIDE-SYNTHESIS; UNNATURAL BIOPOLYMER; COUPLING REAGENTS; ORGANIC-SYNTHESIS; CURTIUS REACTION; RIBONUCLEASE-A; DERIVATIVES;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Conversion of acids to acyl azides using peptide coupling agent TBTU has been demonstrated. The procedure is simple and applicable to a range of carboxylic acids under mild reaction conditions. The protocol is extended to the synthesis of urethane protected amino acid azides as well.
引用
收藏
页码：103 / 109
页数：7
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