Application of 2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate (TBTU) for the synthesis of acid azides

被引：0

作者：

Naik, Shankar A. ^{[1
]}

Lalithamba, H. S. ^{[1
]}

Sureshbabu, Vommina V. ^{[1
]}

机构：

[1] Bangalore Univ, Peptide Res Lab, Dept Studies Chem, Bangalore 560001, Karnataka, India

来源：

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2011年 / 50卷 / 01期

关键词：

Acid chlorides; acyl azides; peptide coupling agent; TBTU; AMINO-ACIDS; ACYL AZIDES; EFFICIENT SYNTHESIS; PEPTIDE-SYNTHESIS; UNNATURAL BIOPOLYMER; COUPLING REAGENTS; ORGANIC-SYNTHESIS; CURTIUS REACTION; RIBONUCLEASE-A; DERIVATIVES;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Conversion of acids to acyl azides using peptide coupling agent TBTU has been demonstrated. The procedure is simple and applicable to a range of carboxylic acids under mild reaction conditions. The protocol is extended to the synthesis of urethane protected amino acid azides as well.

引用

页码：103 / 109

页数：7

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