Elucidating the anti-Staphylococcus aureus antibody response by immunoproteomics

被引：5

作者：

Stentzel, Sebastian ^{[1
]}

Glaeser, Regine ^{[2
]}

Broeker, Barbara M. ^{[1
]}

机构：

[1] Univ Med Greifswald, Dept Immunol, Greifswald, Germany

[2] Univ Hosp Schleswig Holstein, Dept Dermatol, Kiel, Germany

来源：

PROTEOMICS CLINICAL APPLICATIONS | 2016年 / 10卷 / 9-10期

关键词：

1D immunoblots; 2D immunoblots; Antibacterial antibodies; Protein array; Suspension array; TOXIC-SHOCK-SYNDROME; PANTON-VALENTINE LEUKOCIDIN; HUMORAL IMMUNE-RESPONSE; PROTEIN-A; STRUCTURAL BASIS; NASAL CARRIERS; US HOSPITALS; VACCINE; BACTEREMIA; RESISTANT;

D O I：

10.1002/prca.201600050

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Staphylococcus aureus is a notorious pathogen both in-and outside hospitals as well as a frequent colonizer in healthy individuals. Immunoproteomics techniques have been employed to shed light on the human adaptive immune response to S. aureus in health and disease. Since priming of immune memory, a key property of the adaptive immune system, is the basis of successful vaccination, immunoproteomics holds promise for paving the way to an effective S. aureus vaccine.

引用

页码：1011 / 1019

页数：9

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