Farnesol-induced cell death in the filamentous fungus Aspergillus nidulans

被引：12

作者：

Dinamarco, Taisa Magnani ^{[1
]}

Goldman, Maria Helena S. ^{[2
]}

Goldman, Gustavo Henrique ^{[1
,3
]}

机构：

[1] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, Sao Paulo, Brazil

[2] Univ Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, Sao Paulo, Brazil

[3] Lab Nacl Ciencia & Tecnol Bioetanol CTBE, BR-13083970 Campinas, SP, Brazil

来源：

BIOCHEMICAL SOCIETY TRANSACTIONS | 2011年 / 39卷

基金：

巴西圣保罗研究基金会;

关键词：

OXIDATIVE STRESS; ENDONUCLEASE-G; SACCHAROMYCES-CEREVISIAE; ELECTRON-TRANSPORT; INDUCED APOPTOSIS; MITOCHONDRIA; RESPIRATION; INHIBITION; INVOLVEMENT; METABOLISM;

D O I：

10.1042/BST0391544

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

FOH (farnesol), a non-sterol isoprenoid produced by dephosphorylation of farnesyl pyrophosphate, has been shown to inhibit proliferation and induce apoptosis. We have been using Aspergillus nidulans and FOH as a model system and cell death stimulus, respectively, aiming to understand by which means filamentous fungi are driven towards cell death. Here, we review some of our findings about FOH-induced cell death in A. nidulans.

引用

页码：1544 / 1548

页数：5

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