The Impact of Letermovir (LTV) Prophylaxis on Early Cytomegalovirus Infection (CMVi) and Outcomes in the Adult Allogeneic Hematopoietic Cell Transplantation (alloHCT) Recipients with High- Risk Donor Type

被引:0
|
作者
Dadwal, Sanjeet S. [1 ]
Yang, Dongyun [2 ]
Marcucci, Guido [3 ]
Mokhtari, Sally [4 ]
Tegtmeier, Bernard [5 ]
Palmer, Joycelynne [6 ]
Smith, Eileen P. [7 ]
Taplitz, Randy [1 ]
Artz, Andrew S. [8 ]
Curtin, Peter T. [7 ]
Spielberger, Ricardo [7 ,9 ]
Salhotra, Amandeep [7 ]
Stein, Anthony S. [10 ]
Forman, Stephen J. [11 ]
Al Malki, Monzr M. [7 ]
Nakamura, Ryotaro [12 ]
机构
[1] City Hope Natl Med Ctr, Div Infect Dis, 1500 E Duarte Rd, Duarte, CA 91010 USA
[2] City Hope Natl Med Ctr, Dept Computat & Quantitat Med, 1500 E Duarte Rd, Duarte, CA 91010 USA
[3] City Hope Natl Med Ctr, Beckman Res Inst, Dept Hematol Malignancies Translat Sci, Gehr Family Ctr Leukemia Res,Hematol Malignancies, Duarte, CA 91010 USA
[4] City Hope Natl Med Ctr, Dept Clin Translat Program Dev, 1500 E Duarte Rd, Duarte, CA 91010 USA
[5] City Hope Natl Med Ctr, Dept Qual Risk & Regulatory Management, 1500 E Duarte Rd, Duarte, CA 91010 USA
[6] City Hope Natl Med Ctr, Dept Computat & Quantitat Med BRI, 1500 E Duarte Rd, Duarte, CA 91010 USA
[7] City Hope Natl Med Ctr, Dept Hematol HCT, 1500 E Duarte Rd, Duarte, CA 91010 USA
[8] City Hope Natl Med Ctr, Dept Hematol HCT, Duarte, CA USA
[9] Southern Calif Kaiser Permanente, Bone Marrow Transplant Program, Los Angeles, CA USA
[10] City Hope Natl Med Ctr, 1500 E Duarte Rd, Duarte, CA 91010 USA
[11] City Hope Natl Med Ctr, Beckman Res Inst, Dept Hematol HCT, Duarte, CA USA
[12] City Hope Natl Med Ctr, Dept Hematol & Hematopoiet Cell Transplantat, Duarte, CA USA
关键词
D O I
10.1182/blood-2021-153784
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
1776
引用
收藏
页码:1776 / +
页数:6
相关论文
共 50 条
  • [21] IMMUNOGLOBULIN PROPHYLAXIS AGAINST CYTOMEGALOVIRUS INFECTION IN PATIENTS AT HIGH RISK OFINFECTION FOLLOWING ALLOGENEIC HEMATOPOIETIC CELL TRANSPLANTATION
    Ichihara, H.
    Nakamae, H.
    Hirose, A.
    Nakane, T.
    Koh, H.
    Hayashi, Y.
    Nisimoto, M.
    Nakamae, M.
    Terada, Y.
    Koh, S.
    Yoshimura, T.
    Aimoto, M.
    Manabe, M.
    Hagiwara, K.
    Hino, M.
    ANNALS OF ONCOLOGY, 2012, 23 : 167 - 167
  • [22] Letermovir for Secondary Prophylaxis of Cytomegalovirus Infection and Disease after Allogeneic Hematopoietic Cell Transplantation: Results from the French Compassionate Program
    Robin, Christine
    Thiebaut, Anne
    Alain, Sophie
    de Fontbrune, Flore Sicre
    Berceanu, Ana
    D'Aveni, Maud
    Ceballos, Patrice
    Redjoul, Rabah
    Nguyen-Quoc, Stephanie
    Benard, Nathalie
    Pahlavan-Grumel, Golriz
    Cordonnier, Catherine
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2020, 26 (05) : 978 - 984
  • [23] Letermovir for Prevention of Cytomegalovirus Reactivation in Haploidentical and Mismatched Adult Donor Allogeneic Hematopoietic Cell Transplantation with Post-Transplantation Cyclophosphamide for Graft-versus-Host Disease Prophylaxis
    Lin, Andrew
    Flynn, Jessica
    DeRespiris, Lauren
    Figgins, Bradley
    Griffin, Meagan
    Lau, Carmen
    Proli, Anthony
    Devlin, Sean M.
    Cho, Christina
    Tamari, Roni
    Jakubowski, Ann A.
    Papadopoulos, Esperanza B.
    Giralt, Sergio A.
    Perales, Miguel-Angel
    Seo, Susan K.
    Shaffer, Brian
    TRANSPLANTATION AND CELLULAR THERAPY, 2021, 27 (01):
  • [24] Cost-effectiveness analysis of the use of letermovir for the prophylaxis of cytomegalovirus in adult cytomegalovirus seropositive recipients undergoing allogenic hematopoietic stem cell transplantation in Italy
    Restelli, Umberto
    Croce, Davide
    Pacelli, Valeria
    Ciceri, Fabio
    Girmenia, Corrado
    INFECTION AND DRUG RESISTANCE, 2019, 12 : 1127 - 1138
  • [25] Impact of Donor Age and Donor Cytomegalovirus Serostatus on Outcomes After Related Donor Allogeneic Hematopoietic Stem Cell Transplantation
    Mehta, Rohtesh S.
    Choe, Hannah
    Saultz, Jennifer
    Gong, Zimu
    Sharma, Prashant
    Al-Juhaishi, Taha
    Petitto, Gabriela S.
    Lazaryan, Aleksandr
    Singh, Anurag
    Xue, Elisabetta
    Dimitrova, Dimana
    Hyder, Mustafa
    Mccurdy, Shannon
    Im, Annie
    Huber, Bryan
    Aljawai, Yosra M.
    Kanakry, Jennifer
    Milano, Filippo
    Kanakry, Christopher G.
    AMERICAN JOURNAL OF HEMATOLOGY, 2025,
  • [26] Impact of Letermovir Primary Cytomegalovirus Prophylaxis on 1-Year Mortality After Allogeneic Hematopoietic Cell Transplantation: A Retrospective Cohort Study
    Su, Yiqi
    Stern, Anat
    Karantoni, Eleni
    Nawar, Tamara
    Han, Gyuri
    Zavras, Phaedon
    Dumke, Henry
    Cho, Christina
    Tamari, Roni
    Shaffer, Brian
    Giralt, Sergio
    Jakubowski, Ann
    Perales, Miguel-Angel
    Papanicolaou, Genovefa
    CLINICAL INFECTIOUS DISEASES, 2022, 75 (05) : 795 - 804
  • [27] Letermovir (LET) for prevention of cytomegalovirus (CMV) infection: results from a phase III randomized, double-blind, placebo (PBO)-controlled trial in adult allogeneic hematopoietic cell transplant (alloHCT) recipients
    Ljungman, P.
    Marty, F. M.
    Chemaly, R. F.
    Maertens, J.
    Duarte, R. F.
    Teal, V. L.
    Wan, H.
    Kartsonis, N. A.
    Leavitt, R. Y.
    Badshah, C.
    BONE MARROW TRANSPLANTATION, 2017, 52 : S11 - S12
  • [28] Human Cytomegalovirus-Specific T-Cell Reconstitution and Late-Onset Cytomegalovirus Infection in Hematopoietic Stem Cell Transplantation Recipients following Letermovir Prophylaxis
    Gabanti, Elisa
    Borsani, Oscar
    Colombo, Anna Amelia
    Zavaglio, Federica
    Binaschi, Luana
    Caldera, Daniela
    Sciarra, Roberta
    Cassinelli, Gabriela
    Alessandrino, Emilio Paolo
    Bernasconi, Paolo
    Ferretti, Virginia Valeria
    Lilleri, Daniele
    Baldanti, Fausto
    TRANSPLANTATION AND CELLULAR THERAPY, 2022, 28 (04): : 211.e1 - 211.e9
  • [29] Impact of Primary Letermovir Prophylaxis Versus Preemptive Antiviral Therapy for Cytomegalovirus on Economic and Clinical Outcomes after Hematopoietic Cell Transplantation
    Tan, Carrie A.
    Palen, Lauren
    Su, Yiqi
    Li, Yuxuan
    Gennarelli, Renee L.
    Perales, Miguel-Angel
    Cohen, Nina
    Papanicolaou, Genovefa A.
    Shah, Gunjan L.
    Seo, Susan K.
    TRANSPLANTATION AND CELLULAR THERAPY, 2024, 30 (08): : 792e1 - 792e12
  • [30] Real World Outcomes of Letermovir Prophylaxis in Unselected High Risk CMV Seropositive Hematopoietic Stem Cell Transplant Recipients
    Karam, Eva
    LaPorte, Justin
    Sizemore, Connie
    Zhang, Xu
    Holland, H. Kent
    Solh, Melhem
    Morris, Lawrence E.
    Bashey, Asad
    Solomon, Scott R.
    BLOOD, 2019, 134