Epidermal growth factor receptor-targeted treatment for advanced colorectal carcinoma

被引：71
|
作者：
Venook, AP [1 ]
机构：
[1] Univ Calif San Francisco, Dept Med, San Francisco, CA 94115 USA
来源：
CANCER | 2005年 / 103卷 / 12期
关键词：
colorectal carcinoma; epidermal growth factor receptor; IMC-C225; cetuximab; bevacizumab; targeted chemotherapy;
D O I：
10.1002/cncr.21123
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Substantial effort has focused on the development of novel targeted agents for treating patients with late-stage colorectal carcinoma. These agents are designed specifically to inhibit biochemical processes associated with pathogenesis. Numerous molecules targeting the epidermal growth factor receptor have been investigated as therapeutic agents and appear to herald a shift in the treatment paradigm for colorectal carcinoma. (c) 2005 American Cancer Society.
引用
收藏
页码：2435 / 2446
页数：12
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