Advances in atopic dermatitis

被引：59
|
作者：
Novak, Natalija [2 ]
Leung, Donald Y. M. [1 ]
机构：
[1] Natl Jewish Hlth, Dept Pediat, Denver, CO 80206 USA
[2] Univ Bonn, Dept Dermatol & Allergy, D-53105 Bonn, Germany
来源：
CURRENT OPINION IN IMMUNOLOGY | 2011年 / 23卷 / 06期
关键词：
ECZEMA HERPETICUM; DENDRITIC CELLS; FILAGGRIN MUTATIONS; IMMUNE-RESPONSES; CHROMOSOME; 11Q13; T-CELLS; SKIN; RISK; VARIANT; SUSCEPTIBILITY;
D O I：
10.1016/j.coi.2011.09.007
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Atopic dermatitis (AD) results from barrier defects combined with modified immune responses of the innate and the adaptive immune system to exogenous and endogenous factors. Recent research has continued to sort out the complex pathophysiologic puzzle of this frequent skin disease. However, the network of mechanisms leading to the manifestation of AD is far from being completely understood.
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页码：778 / 783
页数：6
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